Curated Information
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Home > Curated Information Page > Cst Curation Set #9512
Tucker M (2010) CST Curation Set: 9512; Year: 2010; Biosample/Treatment: tissue, breast/untreated; Disease: breast cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y413-p - AFAP1L2 (human)
Modsite: DPsPDHLysFRILHK SwissProt Entrez-Gene
Orthologous residues
AFAP1L2 (human): Y413‑p, AFAP1L2 iso2 (human): Y413‑p, AFAP1L2 iso4 (human): Y441‑p, AFAP1L2 (mouse): Y413‑p, AFAP1L2 (rat): Y414‑p, AFAP1L2 (cow): Y413‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y15-p - CDK1 (human)
Modsite: EkIGEGtyGVVykGR SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): Y15‑p, CDK1 iso2 (human): Y15‑p, CDK1 (mouse): Y15‑p, CDK1 (rat): Y15‑p, CDK1 (chicken): Y15‑p, CDK1 (fruit fly): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y15-p - CDK2 (human)
Modsite: EkIGEGtyGVVykAR SwissProt Entrez-Gene
Orthologous residues
CDK2 (human): Y15‑p, CDK2 iso2 (human): Y15‑p, CDK2 (mouse): Y15‑p, CDK2 (rat): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y15-p - CDK3 (human)
Modsite: EkIGEGtyGVVyKAK SwissProt Entrez-Gene
Orthologous residues
CDK3 (human): Y15‑p, CDK3 (mouse): Y15‑p, CDK3 (cow): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y321-p - DYRK1A (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1A (human): Y321‑p, DYRK1A iso2 (human): Y312‑p, DYRK1A iso4 (human): Y321‑p, DYRK1A (mouse): Y321‑p, DYRK1A (rat): Y321‑p, DYRK1A (rabbit):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y273-p - DYRK1B (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1B (human): Y273‑p, DYRK1B iso2 (human): Y273‑p, DYRK1B (mouse): Y273‑p, DYRK1B (rat): Y273‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y243-p - eIF3-alpha (human)
Modsite: MkDDLADyGGyDGGy SwissProt Entrez-Gene
Orthologous residues
eIF3‑alpha (human): Y243‑p, eIF3‑alpha (mouse): Y246‑p, eIF3‑alpha (rat): Y244‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y254-p - eIF3-alpha (human)
Modsite: DGGyVQDyEDFM___ SwissProt Entrez-Gene
Orthologous residues
eIF3‑alpha (human): Y254‑p, eIF3‑alpha (mouse): Y257‑p, eIF3‑alpha (rat): Y255‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y204-p - ERK1 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): Y204‑p, ERK1 iso2 (human): Y204‑p, ERK1 iso3 (human): Y204‑p, ERK1 (mouse): Y205‑p, ERK1 (rat): Y205‑p, ERK1 (hamster): Y194‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

T185-p - ERK2 (human)
Modsite: HDHtGFLtEyVAtRW SwissProt Entrez-Gene
Orthologous residues
ERK2 (human): T185‑p, ERK2 (mouse): T183‑p, ERK2 (rat): T183‑p, ERK2 (chicken): T193‑p, ERK2 (cow): T185‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y187-p - ERK2 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK2 (human): Y187‑p, ERK2 (mouse): Y185‑p, ERK2 (rat): Y185‑p, ERK2 (chicken): Y195‑p, ERK2 (cow): Y187‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y46-p - FRK (human)
Modsite: QsQRHGHyFVALFDy SwissProt Entrez-Gene
Orthologous residues
FRK (human): Y46‑p, FRK (mouse): Y53‑p, FRK (rat): Y47‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y420-p - Fyn (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Fyn (human): Y420‑p, Fyn iso2 (human): Y417‑p, Fyn iso3 (human): Y365‑p, Fyn (mouse): Y420‑p, Fyn (rat): Y420‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y659-p - GAB1 (human)
Modsite: VADERVDyVVVDQQK SwissProt Entrez-Gene
Orthologous residues
GAB1 (human): Y659‑p, GAB1 iso2 (human): Y689‑p, GAB1 (mouse): Y660‑p, GAB1 (rat): Y658‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y1105-p - GRF-1 (human)
Modsite: RNEEENIysVPHDst SwissProt Entrez-Gene
Orthologous residues
GRF‑1 (human): Y1105‑p, GRF‑1 (mouse): Y1105‑p, GRF‑1 (rat): Y1105‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y279-p - GSK3A (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3A (human): Y279‑p, GSK3A (mouse): Y279‑p, GSK3A (rat): Y279‑p, GSK3A (cow): Y279‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y216-p - GSK3B (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): Y216‑p, GSK3B iso2 (human): Y216‑p, GSK3B (mouse): Y216‑p, GSK3B (rat): Y216‑p, GSK3B (rabbit): Y216‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y352-p - HIPK1 (human)
Modsite: SkAVCstyLQsRYYR SwissProt Entrez-Gene
Orthologous residues
HIPK1 (human): Y352‑p, HIPK1 iso2 (human): Y352‑p, HIPK1 iso4 (human): , HIPK1 (mouse): Y352‑p, HIPK1 (rat): Y352‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y361-p - HIPK2 (human)
Modsite: SkAVCstyLQsRYyR SwissProt Entrez-Gene
Orthologous residues
HIPK2 (human): Y361‑p, HIPK2 (mouse): Y361‑p, HIPK2 (rat): Y361‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y359-p - HIPK3 (human)
Modsite: SkTVCstyLQsRYYR SwissProt Entrez-Gene
Orthologous residues
HIPK3 (human): Y359‑p, HIPK3 iso2 (human): Y359‑p, HIPK3 (mouse): Y359‑p, HIPK3 (rat): Y359‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y394-p - Lck (human)
Modsite: RLIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
Lck (human): Y394‑p, Lck iso3 (human): Y424‑p, Lck (mouse): Y394‑p, Lck (rat): Y394‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y182-p - P38A (human)
Modsite: tDDEMtGyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
P38A (human): Y182‑p, P38A iso2 (human): Y182‑p, P38A (mouse): Y182‑p, P38A iso3 (mouse): Y182‑p, P38A (rat): Y182‑p, P38A (salmonid): Y183‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

S1501-p - PHIP (human)
Modsite: INGktEsssVVRTRs SwissProt Entrez-Gene
Orthologous residues
PHIP (human): S1501‑p, PHIP (mouse): S1501‑p, PHIP (rat): S1096‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y467-p - PIK3R1 (human)
Modsite: SREyDRLyEEytRTS SwissProt Entrez-Gene
Orthologous residues
PIK3R1 (human): Y467‑p, PIK3R1 iso2 (human): Y197‑p, PIK3R1 iso4 (human): Y467‑p, PIK3R1 (mouse): Y467‑p, PIK3R1 (rat): Y467‑p, PIK3R1 (cow): Y467‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y849-p - PRP4 (human)
Modsite: ADNDItPyLVsRFyR SwissProt Entrez-Gene
Orthologous residues
PRP4 (human): Y849‑p, PRP4 (mouse): Y849‑p, PRP4 (rat): Y849‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y798-p - PTPRA (human)
Modsite: yIDAFsDyANFK___ SwissProt Entrez-Gene
Orthologous residues
PTPRA (human): Y798‑p, PTPRA iso2 (human): Y789‑p, PTPRA (mouse): Y825‑p, PTPRA (rat): Y792‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y118-p - PXN (human)
Modsite: VGEEEHVysFPNkQk SwissProt Entrez-Gene
Orthologous residues
PXN (human): Y118‑p, PXN iso2 (human): Y118‑p, PXN iso3 (human): Y118‑p, PXN (mouse): Y118‑p, PXN iso2 (mouse): Y118‑p, PXN (rat): Y118‑p, PXN (chicken): Y118‑p, PXN (cow): Y112‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y419-p - Src (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Src (human): Y419‑p, Src iso2 (human): Y425‑p, Src (mouse): Y424‑p, Src iso2 (mouse): Y418‑p, Src (rat): Y419‑p, Src (chicken): Y416‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y705-p - STAT3 (human)
Modsite: DPGsAAPyLktKFIC SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y694-p - STAT5A (human)
Modsite: LAkAVDGyVkPQIkQ SwissProt Entrez-Gene
Orthologous residues
STAT5A (human): Y694‑p, STAT5A (mouse): Y694‑p, STAT5A iso2 (mouse): , STAT5A (rat): Y694‑p, STAT5A (fruit fly): Y711‑p, STAT5A (sheep): Y694‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y699-p - STAT5B (human)
Modsite: tAkAVDGyVkPQIkQ SwissProt Entrez-Gene
Orthologous residues
STAT5B (human): Y699‑p, STAT5B (mouse): Y699‑p, STAT5B (rat): Y699‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y483-p - tensin 2 (human)
Modsite: GPLDGsPyAQVQRPP SwissProt Entrez-Gene
Orthologous residues
tensin 2 (human): Y483‑p, tensin 2 iso2 (human): Y483‑p, tensin 2 iso4 (human): Y493‑p, tensin 2 (mouse): Y483‑p, tensin 2 (rat): Y483‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample

Y426-p - Yes (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Yes (human): Y426‑p, Yes (mouse): Y424‑p, Yes (rat): Y424‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer, breast cancer, surrounding tissue
Relevant cell lines - cell types - tissues:  breast
Cellular systems studied:  tissue
Species studied:  human
Comments:  adjacent, normal control for breast cancer sample