Curated Information
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Home > Curated Information Page > PubMed Id: 20560669
Chan LS, Hansra G, Robinson PJ, Graham ME (2010) Differential phosphorylation of dynamin I isoforms in subcellular compartments demonstrates the hidden complexity of phosphoproteomes. J Proteome Res 9, 4028-37 20560669
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S774-p - DYN1 (rat)
Modsite: SVPAGRRsPTSsPTP SwissProt Entrez-Gene
Orthologous residues
DYN1 (human): S774‑p, DYN1 iso2 (human): S774‑p, DYN1 iso3 (human): S774‑p, DYN1 (mouse): S774‑p, DYN1 iso3 (mouse): S774‑p, DYN1 iso4 (mouse): S774‑p, DYN1 iso6 (mouse): S770‑p, DYN1 (rat): S774‑p, DYN1 iso2 (rat): S774‑p
Characterization
Methods used to characterize site in vivo [32P] bio-synthetic labeling, mass spectrometry, western blotting
Relevant cell lines - cell types - tissues:  brain, neuron:synaptosome
Cellular systems studied:  primary cells, tissue
Species studied:  rat
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
depolarization decrease

S778-p - DYN1 (rat)
Modsite: GRRsPTSsPTPQRRA SwissProt Entrez-Gene
Orthologous residues
DYN1 (human): S778‑p, DYN1 iso2 (human): S778‑p, DYN1 iso3 (human): S778‑p, DYN1 (mouse): S778‑p, DYN1 iso3 (mouse): S778‑p, DYN1 iso4 (mouse): S778‑p, DYN1 iso6 (mouse): S774‑p, DYN1 (rat): S778‑p, DYN1 iso2 (rat): S778‑p
Characterization
Methods used to characterize site in vivo [32P] bio-synthetic labeling, mass spectrometry, western blotting
Relevant cell lines - cell types - tissues:  brain, neuron:synaptosome
Cellular systems studied:  primary cells, tissue
Species studied:  rat
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
depolarization decrease

S851-p - DYN1 (rat)
Modsite: PSRSGQAsPSRPEsP SwissProt Entrez-Gene
Orthologous residues
DYN1 (human): S851‑p, DYN1 iso2 (human): S851‑p, DYN1 iso3 (human): , DYN1 (mouse): S853‑p, DYN1 iso3 (mouse): , DYN1 iso4 (mouse): S851‑p, DYN1 iso6 (mouse): , DYN1 (rat): S851‑p, DYN1 iso2 (rat):
Characterization
Methods used to characterize site in vivo [32P] bio-synthetic labeling, mass spectrometry, western blotting
Relevant cell lines - cell types - tissues:  brain, neuron:synaptosome
Cellular systems studied:  primary cells, tissue
Species studied:  rat
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
depolarization decrease

S857-p - DYN1 (rat)
Modsite: AsPSRPEsPRPPFDL SwissProt Entrez-Gene
Orthologous residues
DYN1 (human): S857‑p, DYN1 iso2 (human): S857‑p, DYN1 iso3 (human): , DYN1 (mouse): E859‑p, DYN1 iso3 (mouse): , DYN1 iso4 (mouse): S857‑p, DYN1 iso6 (mouse): A853‑p, DYN1 (rat): S857‑p, DYN1 iso2 (rat):
Characterization
Methods used to characterize site in vivo [32P] bio-synthetic labeling, mass spectrometry, western blotting
Relevant cell lines - cell types - tissues:  brain, neuron:synaptosome
Cellular systems studied:  primary cells, tissue
Species studied:  rat
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
depolarization decrease

S774-p - DYN1 iso2 (rat)
Modsite: SVPAGRRsPTSsPTP SwissProt
Orthologous residues
DYN1 (human): S774‑p, DYN1 iso2 (human): S774‑p, DYN1 iso3 (human): S774‑p, DYN1 (mouse): S774‑p, DYN1 iso3 (mouse): S774‑p, DYN1 iso4 (mouse): S774‑p, DYN1 iso6 (mouse): S770‑p, DYN1 (rat): S774‑p, DYN1 iso2 (rat): S774‑p
Characterization
Methods used to characterize site in vivo [32P] bio-synthetic labeling, mass spectrometry, western blotting
Relevant cell lines - cell types - tissues:  brain, neuron:synaptosome
Cellular systems studied:  primary cells, tissue
Species studied:  rat
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
depolarization decrease

S778-p - DYN1 iso2 (rat)
Modsite: GRRsPTSsPTPQRRA SwissProt
Orthologous residues
DYN1 (human): S778‑p, DYN1 iso2 (human): S778‑p, DYN1 iso3 (human): S778‑p, DYN1 (mouse): S778‑p, DYN1 iso3 (mouse): S778‑p, DYN1 iso4 (mouse): S778‑p, DYN1 iso6 (mouse): S774‑p, DYN1 (rat): S778‑p, DYN1 iso2 (rat): S778‑p
Characterization
Methods used to characterize site in vivo [32P] bio-synthetic labeling, mass spectrometry, western blotting
Relevant cell lines - cell types - tissues:  brain, neuron:synaptosome
Cellular systems studied:  primary cells, tissue
Species studied:  rat
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
depolarization decrease