Curated Information
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Home > Curated Information Page > PubMed Id: 31152145
Sueyoshi T, et al. (2019) A phosphorylation-deficient mutant of retinoid X receptor α at Thr 167 alters fasting response and energy metabolism in mice. Lab Invest 31152145
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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T167-p - RXRA (mouse)
Modsite: CKGFFKRtVRKDLTY SwissProt Entrez-Gene
Orthologous residues
RXRA (human): T162‑p, RXRA (mouse): T167‑p, RXRA (rat): T167‑p
Characterization
Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
Disease tissue studied:  brain cancer, glioblastoma, glioma
Relevant cell lines - cell types - tissues:  adipose tissue, liver, muscle, U87MG (glial)
Cellular systems studied:  cell lines, tissue
Species studied:  human, mouse
Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKCA (mouse)
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
fasting increase