Klenova EM, et al. (2001) Functional phosphorylation sites in the C-terminal region of the multivalent multifunctional transcriptional factor CTCF. Mol Cell Biol 21, 2221-34 11238955

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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S604-p - CTCF (chicken) ▲

Modsite: GRKRKMRsKKEDssD SwissProt Entrez-Gene Orthologous residues CTCF (human): S604‑p, CTCF (mouse): S604‑p, CTCF (rat): S604‑p, CTCF (chicken): S604‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mutation of modification site, phosphoamino acid analysis, phosphopeptide mapping Relevant cell lines - cell types - tissues:  COS (fibroblast), HD3 Cellular systems studied:  cell lines Species studied:  chicken, green monkey Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK2A1 (human) Downstream Regulation Effect of modification (process):  cell growth, altered, transcription, altered

S609-p - CTCF (chicken) ▲

Modsite: MRsKKEDssDsEENA SwissProt Entrez-Gene Orthologous residues CTCF (human): S609‑p, CTCF (mouse): S609‑p, CTCF (rat): S609‑p, CTCF (chicken): S609‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mutation of modification site, phosphoamino acid analysis, phosphopeptide mapping Relevant cell lines - cell types - tissues:  COS (fibroblast), HD3 Cellular systems studied:  cell lines Species studied:  chicken, green monkey Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK2A1 (human) Downstream Regulation Effect of modification (process):  cell growth, altered, transcription, altered

S610-p - CTCF (chicken) ▲

Modsite: RsKKEDssDsEENAE SwissProt Entrez-Gene Orthologous residues CTCF (human): S610‑p, CTCF (mouse): S610‑p, CTCF (rat): S610‑p, CTCF (chicken): S610‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mutation of modification site, phosphoamino acid analysis, phosphopeptide mapping Relevant cell lines - cell types - tissues:  COS (fibroblast), HD3 Cellular systems studied:  cell lines Species studied:  chicken, green monkey Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK2A1 (human) Downstream Regulation Effect of modification (process):  cell growth, altered, transcription, altered

S612-p - CTCF (chicken) ▲

Modsite: KKEDssDsEENAEPD SwissProt Entrez-Gene Orthologous residues CTCF (human): S612‑p, CTCF (mouse): S612‑p, CTCF (rat): S612‑p, CTCF (chicken): S612‑p Characterization Methods used to characterize site in vivo:  [32P] bio-synthetic labeling, mutation of modification site, phosphoamino acid analysis, phosphopeptide mapping Relevant cell lines - cell types - tissues:  COS (fibroblast), HD3 Cellular systems studied:  cell lines Species studied:  chicken, green monkey Enzymes shown to modify site in vitro:  Type Enzyme KINASE CK2A1 (human) Downstream Regulation Effect of modification (process):  cell growth, altered, transcription, altered