Cazaubon S, Bornancin F, Parker PJ (1994) Threonine-497 is a critical site for permissive activation of protein kinase C alpha. Biochem J 301 ( Pt 2), 443-8 8042986

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T494-p - PKCA (cow) ▲
Modsite: EHMMDGVttRtFCGT SwissProt Entrez-Gene Orthologous residues PKCA (human): T494‑p, PKCA (mouse): T494‑p, PKCA (rat): T494‑p, PKCA (cow): T494‑p Characterization Methods used to characterize site in vivo:  mutation of modification site, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  COS (fibroblast) Cellular systems studied:  cell lines

T495-p - PKCA (cow) ▲
Modsite: HMMDGVttRtFCGTP SwissProt Entrez-Gene Orthologous residues PKCA (human): T495‑p, PKCA (mouse): T495‑p, PKCA (rat): T495‑p, PKCA (cow): T495‑p Characterization Methods used to characterize site in vivo:  mutation of modification site, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  COS (fibroblast) Cellular systems studied:  cell lines

T497-p - PKCA (cow) ▲

Modsite: MDGVttRtFCGTPDY SwissProt Entrez-Gene Orthologous residues PKCA (human): T497‑p, PKCA (mouse): T497‑p, PKCA (rat): T497‑p, PKCA (cow): T497‑p Characterization Methods used to characterize site in vivo:  mutation of modification site, phospho-antibody, western blotting Relevant cell lines - cell types - tissues:  COS (fibroblast) Cellular systems studied:  cell lines Upstream Regulation Treatments, proteins and their effect on site modification:  Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes phorbol_ester increase Ca(2+) increase Downstream Regulation Effect of modification (function):  enzymatic activity, induced