Curated Information
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Home > Curated Information Page > PubMed Id: 17662724
Esmenjaud-Mailhat C, et al. (2007) Phosphorylation of CDC25C at S263 controls its intracellular localisation. FEBS Lett 581, 3979-85 17662724
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S263-p - CDC25C (human)
Modsite: LCLKkTVsLCDITIT SwissProt Entrez-Gene
Orthologous residues
CDC25C (human): S263‑p, CDC25C iso3 (human): S220‑p, CDC25C (mouse): P236‑p, CDC25C (frog): S343‑p
Characterization
Methods used to characterize site in vivo mass spectrometry, mutation of modification site
Relevant cell lines - cell types - tissues:  U2OS (bone cell) [GR (human)]
Cellular systems studied:  cell lines
Species studied:  human
Downstream Regulation
Effect of modification (function):  intracellular localization
Comments:  negatively regulates translocation from cytoplasm to nucleus