Curated Information
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Home > Curated Information Page > PubMed Id: 17629739
Solan JL, Lampe PD (2007) Key connexin 43 phosphorylation events regulate the gap junction life cycle. J Membr Biol 217, 35-41 17629739
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.
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S262-p - GJA1 (human)
Modsite: sPAkDCGsQkyAyFN SwissProt Entrez-Gene
Orthologous residues
GJA1 (human): S262‑p, GJA1 (mouse): S262‑p, GJA1 (rat): S262‑p, GJA1 (rabbit): S262‑p, GJA1 (pig): S262‑p, GJA1 (hamster): S262‑p, GJA1 (cow): S263‑p
Characterization
Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  CHO (fibroblast), HeLa (cervical), MDCK (epithelial)
Cellular systems studied:  cell lines
Species studied:  dog, hamster, human
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
phorbol_ester increase

S279-p - GJA1 (human)
Modsite: sSPtAPLsPMsPPGy SwissProt Entrez-Gene
Orthologous residues
GJA1 (human): S279‑p, GJA1 (mouse): S279‑p, GJA1 (rat): S279‑p, GJA1 (rabbit): S279‑p, GJA1 (pig): S279‑p, GJA1 (hamster): S279‑p, GJA1 (cow): S280‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  CHO (fibroblast), MDCK (epithelial)
Cellular systems studied:  cell lines
Species studied:  dog, hamster
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
phorbol_ester increase

S282-p - GJA1 (human)
Modsite: tAPLsPMsPPGykLV SwissProt Entrez-Gene
Orthologous residues
GJA1 (human): S282‑p, GJA1 (mouse): S282‑p, GJA1 (rat): S282‑p, GJA1 (rabbit): S282‑p, GJA1 (pig): S282‑p, GJA1 (hamster): S282‑p, GJA1 (cow): S283‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  CHO (fibroblast), MDCK (epithelial)
Cellular systems studied:  cell lines
Species studied:  dog, hamster
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
phorbol_ester increase

S325-p - GJA1 (human)
Modsite: NRMGQAGstIsNsHA SwissProt Entrez-Gene
Orthologous residues
GJA1 (human): S325‑p, GJA1 (mouse): S325‑p, GJA1 (rat): S325‑p, GJA1 (rabbit): S325‑p, GJA1 (pig): S325‑p, GJA1 (hamster): S325‑p, GJA1 (cow): S326‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  CHO (fibroblast), MDCK (epithelial)
Cellular systems studied:  cell lines
Species studied:  dog, hamster

S328-p - GJA1 (human)
Modsite: GQAGstIsNsHAQPF SwissProt Entrez-Gene
Orthologous residues
GJA1 (human): S328‑p, GJA1 (mouse): S328‑p, GJA1 (rat): S328‑p, GJA1 (rabbit): S328‑p, GJA1 (pig): S328‑p, GJA1 (hamster): S328‑p, GJA1 (cow): S329‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  CHO (fibroblast), MDCK (epithelial)
Cellular systems studied:  cell lines
Species studied:  dog, hamster

S330-p - GJA1 (human)
Modsite: AGstIsNsHAQPFDF SwissProt Entrez-Gene
Orthologous residues
GJA1 (human): S330‑p, GJA1 (mouse): S330‑p, GJA1 (rat): S330‑p, GJA1 (rabbit): S330‑p, GJA1 (pig): S330‑p, GJA1 (hamster): S330‑p, GJA1 (cow): S331‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  CHO (fibroblast), MDCK (epithelial)
Cellular systems studied:  cell lines
Species studied:  dog, hamster

S368-p - GJA1 (human)
Modsite: QRPssRAssRAssRP SwissProt Entrez-Gene
Orthologous residues
GJA1 (human): S368‑p, GJA1 (mouse): S368‑p, GJA1 (rat): S368‑p, GJA1 (rabbit): S368‑p, GJA1 (pig): S368‑p, GJA1 (hamster): S368‑p, GJA1 (cow): S369‑p
Characterization
Methods used to characterize site in vivo phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  CHO (fibroblast), MDCK (epithelial)
Cellular systems studied:  cell lines
Species studied:  dog, hamster
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
phorbol_ester increase