Curated Information
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Home > Curated Information Page > PubMed Id: 17569665
Song H, Belcastro M, Young EJ, Sokolov M (2007) Compartment-specific phosphorylation of phosducin in rods underlies adaptation to various levels of illumination. J Biol Chem 282, 23613-21 17569665
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S54-p - phosducin (mouse)
Modsite: KEILRQMsSPQSRDD SwissProt Entrez-Gene
Orthologous residues
phosducin (human): S54‑p, phosducin (mouse): S54‑p, phosducin (rat): S54‑p, phosducin (cow): S54‑p
Characterization
Methods used to characterize site in vivo immunoprecipitation, phospho-antibody
Relevant cell lines - cell types - tissues:  retina
Cellular systems studied:  tissue
Species studied:  mouse
Enzymes shown to modify site in vitro
Type Enzyme
KINASE CAMK2A (human)
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
microcystin-LR increase
okadaic_acid increase
light increase

S71-p - phosducin (mouse)
Modsite: ERMSRKMsIQEYELI SwissProt Entrez-Gene
Orthologous residues
phosducin (human): S73‑p, phosducin (mouse): S71‑p, phosducin (rat): S73‑p, phosducin (cow): S73‑p
Characterization
Methods used to characterize site in vivo immunoprecipitation, phospho-antibody
Relevant cell lines - cell types - tissues:  retina
Cellular systems studied:  tissue
Species studied:  mouse
Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKACA (human)
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
microcystin-LR increase
okadaic_acid increase
light increase

S54-p - phosducin (rat)
Modsite: KEILRQMsSPQSRDD SwissProt Entrez-Gene
Orthologous residues
phosducin (human): S54‑p, phosducin (mouse): S54‑p, phosducin (rat): S54‑p, phosducin (cow): S54‑p
Characterization
Methods used to characterize site in vivo immunoprecipitation, phospho-antibody
Relevant cell lines - cell types - tissues:  retina
Cellular systems studied:  tissue
Species studied:  rat
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
light increase dim light triggers dephosphorylation of this site

S73-p - phosducin (rat)
Modsite: ERMSRKMsIQEYELI SwissProt Entrez-Gene
Orthologous residues
phosducin (human): S73‑p, phosducin (mouse): S71‑p, phosducin (rat): S73‑p, phosducin (cow): S73‑p
Characterization
Methods used to characterize site in vivo immunoprecipitation, phospho-antibody
Relevant cell lines - cell types - tissues:  retina
Cellular systems studied:  tissue
Species studied:  rat
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
light increase saturated light
light decrease dim light