Curated Information
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Home > Curated Information Page > PubMed Id: 17569669
Konishi H, et al. (2007) Identification of peripherin as a Akt substrate in neurons. J Biol Chem 282, 23491-9 17569669
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S66-p - peripherin (mouse)
Modsite: sssArLGsFRAPRAG SwissProt Entrez-Gene
Orthologous residues
peripherin (human): S59‑p, peripherin iso2 (human): S59‑p, peripherin (mouse): S66‑p, peripherin iso3 (mouse): S66‑p, peripherin (rat): S59‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Relevant cell lines - cell types - tissues:  HEK293T (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE Akt1 (human)
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE Akt1 (human) activation of upstream enzyme, co-immunoprecipitation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
LY294002 decrease

S59-p - peripherin (rat)
Modsite: sSSARLGsFRAPRAG SwissProt Entrez-Gene
Orthologous residues
peripherin (human): S59‑p, peripherin iso2 (human): S59‑p, peripherin (mouse): S66‑p, peripherin iso3 (mouse): S66‑p, peripherin (rat): S59‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Relevant cell lines - cell types - tissues:  'neuron, hypoglossal motor'
Cellular systems studied:  primary cells
Species studied:  rat