Curated Information
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Home > Curated Information Page > PubMed Id: 17581920
Feliers D, et al. (2007) Heterogeneous nuclear ribonucleoprotein K contributes to angiotensin II stimulation of vascular endothelial growth factor mRNA translation. Am J Physiol Renal Physiol 293, F607-15 17581920
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S302-p - hnRNP K (mouse)
Modsite: GrGGrGGsrARNLPL SwissProt Entrez-Gene
Orthologous residues
hnRNP K (human): S302‑p, hnRNP K iso2 (human): S302‑p, hnRNP K iso3 (human): S278‑p, hnRNP K (mouse): S302‑p, hnRNP K iso2 (mouse): S302‑p, hnRNP K iso3 (mouse): S278‑p, hnRNP K iso4 (mouse): S278‑p, hnRNP K (rat): S302‑p, hnRNP K (cow): S302‑p
Characterization
Methods used to characterize site in vivo immunoprecipitation, phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  MCT cells (epithelial)
Cellular systems studied:  cell lines
Species studied:  mouse
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
angiotensin_2 increase
PP2 no change compared to control
PP2 angiotensin_2 inhibit treatment-induced increase
Downstream Regulation
Effect of modification (function):  molecular association, regulation
Effect of modification (process):  translation, induced
Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
Induces pull-down assay