Curated Information
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Home > Curated Information Page > PubMed Id: 17535448
Paliwal P, Radha V, Swarup G (2007) Regulation of p73 by Hck through kinase-dependent and independent mechanisms. BMC Mol Biol 8, 45 17535448
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y28-p - p73 (human)
Modsite: SLEPDStyFDLPQSS SwissProt Entrez-Gene
Orthologous residues
p73 (human): Y28‑p, p73 iso2 (human): Y28‑p, p73 iso8 (human): , p73 iso10 (human): , p73 (mouse): Y25‑p
Characterization
Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
Disease tissue studied:  bone cancer
Relevant cell lines - cell types - tissues:  COS (fibroblast), HeLa (cervical), Saos-2 (bone cell)
Cellular systems studied:  cell lines
Species studied:  green monkey
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE Src (human) transfection of inactive enzyme, transfection of wild-type enzyme
KINASE Hck (human) transfection of wild-type enzyme, co-immunoprecipitation