Curated Information
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Home > Curated Information Page > PubMed Id: 17531806
Navarro L, et al. (2007) Identification of a molecular target for the Yersinia protein kinase A. Mol Cell 26, 465-77 17531806
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S53-p - G-alpha(q) (human)
Modsite: GTGEsGksTFIKQMR SwissProt Entrez-Gene
Orthologous residues
G‑alpha(q) (human): S53‑p, G‑alpha(q) (mouse): S53‑p, G‑alpha(q) (rat): S53‑p
Methods used to characterize site in vivo [32P] bio-synthetic labeling, immunoprecipitation, mass spectrometry, mutation of modification site
Relevant cell lines - cell types - tissues:  HEK293-A (epithelial)
Cellular systems studied:  cell lines
Species studied:  human
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE YpkA (bacteria) transfection of wild-type enzyme, transfection of inactive enzyme
Downstream Regulation
Effect of modification (function):  enzymatic activity, inhibited
Comments:  inhibits G-alpha(q) signaling following infection of bacteria Yersinia pseudotuberculosis