Curated Information
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Home > Curated Information Page > PubMed Id: 17260019
Huang P, Senga T, Hamaguchi M (2007) A novel role of phospho-beta-catenin in microtubule regrowth at centrosome. Oncogene 26, 4357-71 17260019
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S33-p - CTNNB1 (human)
Modsite: QQQsyLDsGIHsGAT SwissProt Entrez-Gene
Orthologous residues
CTNNB1 (human): S33‑p, CTNNB1 (mouse): S33‑p, CTNNB1 (rat): S33‑p
Characterization
Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  3Y1 (fibroblast), COS (fibroblast), HFFF-2 (fibroblast)
Cellular systems studied:  cell lines
Species studied:  green monkey, human, rat

S33-p - CTNNB1 (rat)
Modsite: QQQSYLDsGIHsGAT SwissProt Entrez-Gene
Orthologous residues
CTNNB1 (human): S33‑p, CTNNB1 (mouse): S33‑p, CTNNB1 (rat): S33‑p
Characterization
Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
Relevant cell lines - cell types - tissues:  3Y1 (fibroblast), COS (fibroblast), HFFF-2 (fibroblast)
Cellular systems studied:  cell lines
Species studied:  green monkey, human, rat
Upstream Regulation
Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE GSK3B (rat) phospho-antibody, pharmacological inhibitor of upstream enzyme
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
lithium decrease
Downstream Regulation
Effect of modification (function):  intracellular localization, phosphorylation
Effect of modification (process):  cytoskeletal reorganization

S37-p - CTNNB1 (rat)
Modsite: YLDsGIHsGATtTAP SwissProt Entrez-Gene
Orthologous residues
CTNNB1 (human): S37‑p, CTNNB1 (mouse): S37‑p, CTNNB1 (rat): S37‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  3Y1 (fibroblast), COS (fibroblast)
Cellular systems studied:  cell lines
Species studied:  green monkey, rat

T41-p - CTNNB1 (rat)
Modsite: GIHsGATtTAPsLSG SwissProt Entrez-Gene
Orthologous residues
CTNNB1 (human): T41‑p, CTNNB1 (mouse): T41‑p, CTNNB1 (rat): T41‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  3Y1 (fibroblast), COS (fibroblast)
Cellular systems studied:  cell lines
Species studied:  green monkey, rat