Curated Information
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Home > Curated Information Page > PubMed Id: 17361108
Abbas T, Jha S, Sherman NE, Dutta A (2007) Autocatalytic phosphorylation of CDK2 at the activating Thr160. Cell Cycle 6, 843-52 17361108
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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T160-p - CDK2 (human)
Modsite: GVPVRtytHEVVtLW SwissProt Entrez-Gene
Orthologous residues
CDK2 (human): T160‑p, CDK2 iso2 (human): T160‑p, CDK2 (mouse): T160‑p, CDK2 (rat): T160‑p
Characterization
Methods used to characterize site in vivo phospho-antibody
Relevant cell lines - cell types - tissues:  PC3 (prostate cell)
Cellular systems studied:  cell lines
Species studied:  human
Enzymes shown to modify site in vitro
Type Enzyme
KINASE CDK2 (human)
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
seliciclib decrease
mevastatin decrease