Curated Information
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Home > Curated Information Page > Cst Curation Set #2691
Michaud C (2007) CST Curation Set: 2691; Year: 2007; Biosample/Treatment: cell line, MDA-MB-134vi/serum starved; Disease: breast cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y638-p - APLP1 (human)
Modsite: RELQRHGyENPTyRF SwissProt Entrez-Gene
Orthologous residues
APLP1 (human): Y638‑p, APLP1 iso2 (human): Y639‑p, APLP1 (mouse): Y641‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer
Relevant cell lines - cell types - tissues:  MDA-MB-134vi (breast cell)
Cellular systems studied:  cell lines
Species studied:  human

S418-p - Cortactin (human)
Modsite: tEErLPssPVyEDAA SwissProt Entrez-Gene
Orthologous residues
Cortactin (human): S418‑p, Cortactin iso2 (human): S381‑p, Cortactin iso3 (human): S381‑p, Cortactin (mouse): S418‑p, Cortactin (rat): S380‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer
Relevant cell lines - cell types - tissues:  MDA-MB-134vi (breast cell)
Cellular systems studied:  cell lines
Species studied:  human

Y421-p - Cortactin (human)
Modsite: rLPssPVyEDAAsFK SwissProt Entrez-Gene
Orthologous residues
Cortactin (human): Y421‑p, Cortactin iso2 (human): Y384‑p, Cortactin iso3 (human): Y384‑p, Cortactin (mouse): Y421‑p, Cortactin (rat): Y383‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer
Relevant cell lines - cell types - tissues:  MDA-MB-134vi (breast cell)
Cellular systems studied:  cell lines
Species studied:  human

S510-p - EXO1 (human)
Modsite: RSRFFCSsDsTDCVS SwissProt Entrez-Gene
Orthologous residues
EXO1 (human): S510‑p, EXO1 (mouse): S508‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer
Relevant cell lines - cell types - tissues:  MDA-MB-134vi (breast cell)
Cellular systems studied:  cell lines
Species studied:  human

S512-p - EXO1 (human)
Modsite: RFFCSsDsTDCVSNK SwissProt Entrez-Gene
Orthologous residues
EXO1 (human): S512‑p, EXO1 (mouse): D510‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer
Relevant cell lines - cell types - tissues:  MDA-MB-134vi (breast cell)
Cellular systems studied:  cell lines
Species studied:  human

Y420-p - Fyn (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Fyn (human): Y420‑p, Fyn iso2 (human): Y417‑p, Fyn iso3 (human): Y365‑p, Fyn (mouse): Y420‑p, Fyn (rat): Y420‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer
Relevant cell lines - cell types - tissues:  MDA-MB-134vi (breast cell)
Cellular systems studied:  cell lines
Species studied:  human

Y359-p - HIPK3 (human)
Modsite: SkTVCstyLQsRYYR SwissProt Entrez-Gene
Orthologous residues
HIPK3 (human): Y359‑p, HIPK3 iso2 (human): Y359‑p, HIPK3 (mouse): Y359‑p, HIPK3 (rat): Y359‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer
Relevant cell lines - cell types - tissues:  MDA-MB-134vi (breast cell)
Cellular systems studied:  cell lines
Species studied:  human

Y394-p - Lck (human)
Modsite: RLIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
Lck (human): Y394‑p, Lck iso3 (human): Y424‑p, Lck (mouse): Y394‑p, Lck (rat): Y394‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer
Relevant cell lines - cell types - tissues:  MDA-MB-134vi (breast cell)
Cellular systems studied:  cell lines
Species studied:  human

Y234-p - P130Cas (human)
Modsite: AQPEQDEyDIPRHLL SwissProt Entrez-Gene
Orthologous residues
P130Cas (human): Y234‑p, P130Cas iso2 (human): Y252‑p, P130Cas iso6 (human): Y280‑p, P130Cas iso7 (human): Y252‑p, P130Cas iso8 (human): Y234‑p, P130Cas (mouse): Y238‑p, P130Cas (rat): Y332‑p, P130Cas iso2 (rat): Y238‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer
Relevant cell lines - cell types - tissues:  MDA-MB-134vi (breast cell)
Cellular systems studied:  cell lines
Species studied:  human

Y419-p - Src (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Src (human): Y419‑p, Src iso2 (human): Y425‑p, Src (mouse): Y418‑p, Src iso1 (mouse): Y424‑p, Src (rat): Y419‑p, Src (chicken): Y416‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer
Relevant cell lines - cell types - tissues:  MDA-MB-134vi (breast cell)
Cellular systems studied:  cell lines
Species studied:  human

S1327-p - tensin 1 (human)
Modsite: HVAyGGystPEDRRP SwissProt Entrez-Gene
Orthologous residues
tensin 1 (human): S1327‑p, tensin 1 iso2 (human): , tensin 1 (mouse): S1481‑p, tensin 1 (rat): S1500‑p, tensin 1 (cow): S1306‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer
Relevant cell lines - cell types - tissues:  MDA-MB-134vi (breast cell)
Cellular systems studied:  cell lines
Species studied:  human

Y426-p - Yes (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Yes (human): Y426‑p, Yes (mouse): Y424‑p, Yes (rat): Y424‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  breast cancer
Relevant cell lines - cell types - tissues:  MDA-MB-134vi (breast cell)
Cellular systems studied:  cell lines
Species studied:  human