Gu T (2007) CST Curation Set: 2498; Year: 2007; Biosample/Treatment: tissue, bone marrow/-; Disease: acute myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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Y508-p - LYN (human) ▲

Modsite: ytAtEGQyQQQP___ SwissProt Entrez-Gene Orthologous residues LYN (human): Y508‑p, LYN iso2 (human): Y487‑p, LYN (mouse): Y508‑p, LYN iso2 (mouse): Y487‑p, LYN (rat): Y508‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  bone marrow Cellular systems studied:  tissue Species studied:  human

S145-p - NCL (human) ▲

Modsite: KNAKKEDsDEEEDDD SwissProt Entrez-Gene Orthologous residues NCL (human): S145‑p, NCL (mouse): S145‑p, NCL (rat): S145‑p, NCL iso6 (rat): S145‑p, NCL (cow): S145‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  bone marrow Cellular systems studied:  tissue Species studied:  human

S153-p - NCL (human) ▲

Modsite: DEEEDDDsEEDEEDD SwissProt Entrez-Gene Orthologous residues NCL (human): S153‑p, NCL (mouse): D153‑p, NCL (rat): D153‑p, NCL iso6 (rat): D153‑p, NCL (cow): D149‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  bone marrow Cellular systems studied:  tissue Species studied:  human

S247-p - TXNDC1 (human) ▲
Modsite: EADEEDVsEEEAEsK SwissProt Entrez-Gene Orthologous residues TXNDC1 (human): S247‑p, TXNDC1 (mouse): S245‑p, TXNDC1 (rat): S245‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute myelogenous leukemia Relevant cell lines - cell types - tissues:  bone marrow Cellular systems studied:  tissue Species studied:  human