Curated Information
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Home > Curated Information Page > PubMed Id: 10574913
Pitcher JA, et al. (1999) Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases. J Biol Chem 274, 34531-4 10574913
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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S670-p - GRK2 (cow)
Modsite: KMKNKPRsPVVELSK SwissProt Entrez-Gene
Orthologous residues
GRK2 (human): S670‑p, GRK2 (mouse): S670‑p, GRK2 (rat): S670‑p, GRK2 (cow): S670‑p
Methods used to characterize site in vivo mass spectrometry, mutation of modification site
Relevant cell lines - cell types - tissues:  SF9
Cellular systems studied:  cell lines
Species studied:  insect
Enzymes shown to modify site in vitro
Type Enzyme
KINASE ERK1 (human)
Downstream Regulation
Effect of modification (function):  activity, inhibited