Curated Information
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Home > Curated Information Page > Cst Curation Set #1668
Gu T (2006) CST Curation Set: 1668; Year: 2006; Biosample/Treatment: bone marrow, myeloid/-; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y294-p - ACTB (human)
Modsite: VDIRkDLyANtVLsG SwissProt Entrez-Gene
Orthologous residues
ACTB (human): Y294‑p, ACTB (mouse): Y294‑p, ACTB (rat): Y294‑p, ACTB (cow): Y294‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y294-p - ACTG1 (human)
Modsite: VDIRkDLyANtVLsG SwissProt Entrez-Gene
Orthologous residues
ACTG1 (human): Y294‑p, ACTG1 (mouse): Y294‑p, ACTG1 (rat): Y294‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y304-p - arfaptin 1 (human)
Modsite: FQAHkEKyDKMRNDV SwissProt Entrez-Gene
Orthologous residues
arfaptin 1 (human): Y304‑p, arfaptin 1 iso2 (human): Y272‑p, arfaptin 1 (mouse): Y304‑p, arfaptin 1 (rat): Y297‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y972-p - BCOR (human)
Modsite: RIANSAGyVGDRFKC SwissProt Entrez-Gene
Orthologous residues
BCOR (human): Y972‑p, BCoR iso2 (human): Y972‑p, BCOR (mouse): Y977‑p, BCoR iso2 (mouse): Y977‑p, BCoR iso3 (mouse): Y977‑p, BCoR iso4 (mouse): Y977‑p, BCOR (rat): Y975‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y19-p - CDK1 (human)
Modsite: EGtyGVVykGRHkTT SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): Y19‑p, CDK1 iso2 (human): Y19‑p, CDK1 (mouse): Y19‑p, CDK1 (rat): Y19‑p, CDK1 (chicken): Y19‑p, CDK1 (fruit fly): Y19‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y19-p - CDK2 (human)
Modsite: EGtyGVVykARNkLT SwissProt Entrez-Gene
Orthologous residues
CDK2 (human): Y19‑p, CDK2 iso2 (human): Y19‑p, CDK2 (mouse): Y19‑p, CDK2 (rat): Y19‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y19-p - CDK3 (human)
Modsite: EGtyGVVyKAKNRET SwissProt Entrez-Gene
Orthologous residues
CDK3 (human): Y19‑p, CDK3 (mouse): Y19‑p, CDK3 (cow): Y19‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y107-p - CIMAP1D (human)
Modsite: GRSCTPAySMQGRAK SwissProt Entrez-Gene
Orthologous residues
CIMAP1D (human): Y107‑p, CIMAP1D (mouse): Y107‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y214-p - Claudin-3 (human)
Modsite: GAsLGtGyDRKDyV_ SwissProt Entrez-Gene
Orthologous residues
Claudin‑3 (human): Y214‑p, Claudin‑3 (mouse): Y213‑p, Claudin‑3 (rat): Y213‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y204-p - ERK1 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): Y204‑p, ERK1 iso2 (human): Y204‑p, ERK1 iso3 (human): Y204‑p, ERK1 (mouse): Y205‑p, ERK1 (rat): Y205‑p, ERK1 (hamster): Y194‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y187-p - ERK2 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK2 (human): Y187‑p, ERK2 (mouse): Y185‑p, ERK2 (rat): Y185‑p, ERK2 (chicken): Y195‑p, ERK2 (cow): Y187‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y221-p - ERK5 (human)
Modsite: HQyFMtEyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
ERK5 (human): Y221‑p, ERK5 iso2 (human): Y82‑p, ERK5 (mouse): Y221‑p, ERK5 (rat): Y221‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y65-p - FCER1G (human)
Modsite: yEksDGVytGLstRN SwissProt Entrez-Gene
Orthologous residues
FCER1G (human): Y65‑p, FCER1G (mouse): Y65‑p, FCER1G (rat): Y65‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y28-p - FGR (human)
Modsite: LEGDFRSyGAADHyG SwissProt Entrez-Gene
Orthologous residues
FGR (human): Y28‑p, FGR (mouse): Q26‑p, FGR (rat): Q26‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y34-p - FGR (human)
Modsite: SyGAADHyGPDPTKA SwissProt Entrez-Gene
Orthologous residues
FGR (human): Y34‑p, FGR (mouse): Y32‑p, FGR (rat): Y32‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y420-p - Fyn (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Fyn (human): Y420‑p, Fyn iso2 (human): Y417‑p, Fyn iso3 (human): Y365‑p, Fyn (mouse): Y420‑p, Fyn (rat): Y420‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y279-p - GSK3A (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3A (human): Y279‑p, GSK3A (mouse): Y279‑p, GSK3A (rat): Y279‑p, GSK3A (cow): Y279‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y216-p - GSK3B (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): Y216‑p, GSK3B iso2 (human): Y216‑p, GSK3B (mouse): Y216‑p, GSK3B (rat): Y216‑p, GSK3B (rabbit): Y216‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y411-p - Hck (human)
Modsite: RVIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
Hck (human): Y411‑p, Hck iso2 (human): Y390‑p, Hck iso3 (human): Y389‑p, Hck iso4 (human): Y410‑p, Hck (mouse): Y409‑p, Hck (rat): Y409‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y296-p - hnRNP 2H9 (human)
Modsite: GMDNQGGyGsVGrMG SwissProt Entrez-Gene
Orthologous residues
hnRNP 2H9 (human): Y296‑p, hnRNP 2H9 iso2 (human): Y281‑p, hnRNP 2H9 iso3 (human): Y247‑p, hnRNP 2H9 (mouse): Y296‑p, hnRNP 2H9 (rat): Y296‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y331-p - hnRNP A2/B1 (human)
Modsite: srNMGGPyGGGNyGP SwissProt Entrez-Gene
Orthologous residues
hnRNP A2/B1 (human): Y331‑p, hnRNP A2/B1 iso2 (human): Y319‑p, hnRNP A2/B1 (mouse): Y331‑p, hnRNP A2/B1 iso3 (mouse): Y279‑p, hnRNP A2/B1 (rat): Y331‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y504-p - kindlin-3 (human)
Modsite: SAEGLNPyGLVAPRF SwissProt Entrez-Gene
Orthologous residues
kindlin‑3 (human): Y504‑p, kindlin‑3 iso2 (human): Y500‑p, kindlin‑3 (mouse): Y502‑p, kindlin‑3 (rat): Y502‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y394-p - Lck (human)
Modsite: RLIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
Lck (human): Y394‑p, Lck iso3 (human): Y424‑p, Lck (mouse): Y394‑p, Lck (rat): Y394‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y88-p - LST1 (human)
Modsite: KEDPRADyACIAENK SwissProt Entrez-Gene
Orthologous residues
LST1 (human): Y88‑p, LST1 (mouse): Y86‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y397-p - LYN (human)
Modsite: RVIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
LYN (human): Y397‑p, LYN iso2 (human): Y376‑p, LYN (mouse): Y397‑p, LYN iso2 (mouse): Y376‑p, LYN (rat): Y397‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y473-p - LYN (human)
Modsite: ENCPDELyDIMkMCW SwissProt Entrez-Gene
Orthologous residues
LYN (human): Y473‑p, LYN iso2 (human): Y452‑p, LYN (mouse): Y473‑p, LYN iso2 (mouse): Y452‑p, LYN (rat): Y473‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y182-p - P38A (human)
Modsite: tDDEMtGyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
P38A (human): Y182‑p, P38A iso2 (human): Y182‑p, P38A (mouse): Y182‑p, P38A iso3 (mouse): Y182‑p, P38A (rat): Y182‑p, P38A (salmonid): Y183‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y317-p - PAG (human)
Modsite: EEEIsAMyssVNKPG SwissProt Entrez-Gene
Orthologous residues
PAG (human): Y317‑p, PAG (mouse): Y314‑p, PAG (rat): Y314‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y359-p - PAG (human)
Modsite: PssCNDLyAtVKDFE SwissProt Entrez-Gene
Orthologous residues
PAG (human): Y359‑p, PAG (mouse): Y356‑p, PAG (rat): Y351‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y301-p - PDHA1 (human)
Modsite: MsDPGVsyRtREEIQ SwissProt Entrez-Gene
Orthologous residues
PDHA1 (human): Y301‑p, PDHA1 iso2 (human): Y308‑p, PDHA1 iso4 (human): Y339‑p, PDHA1 (mouse): Y301‑p, PDHA1 (rat): Y301‑p, PDHA1 (pig): Y300‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y299-p - PDHA2 (human)
Modsite: MsDPGVsyRtREEIQ SwissProt Entrez-Gene
Orthologous residues
PDHA2 (human): Y299‑p, PDHA2 (mouse): Y302‑p, PDHA2 (rat): Y302‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y77-p - RAB8A (human)
Modsite: FRtITTAyyRGAMGI SwissProt Entrez-Gene
Orthologous residues
RAB8A (human): Y77‑p, RAB8A (mouse): Y77‑p, RAB8A (rat): Y77‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y78-p - RAB8A (human)
Modsite: RtITTAyyRGAMGIM SwissProt Entrez-Gene
Orthologous residues
RAB8A (human): Y78‑p, RAB8A (mouse): Y78‑p, RAB8A (rat): Y78‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y544-p - SIGLEC5 (human)
Modsite: EAPSTTEysEIKTSK SwissProt Entrez-Gene
Orthologous residues
SIGLEC5 (human): Y544‑p, SIGLEC5 (mouse): Y561‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y419-p - Src (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Src (human): Y419‑p, Src iso2 (human): Y425‑p, Src (mouse): Y418‑p, Src iso1 (mouse): Y424‑p, Src (rat): Y419‑p, Src (chicken): Y416‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y705-p - STAT3 (human)
Modsite: DPGsAAPyLktKFIC SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y91-p - TYROBP (human)
Modsite: ITETEsPyQELQGQR SwissProt Entrez-Gene
Orthologous residues
TYROBP (human): Y91‑p, TYROBP iso2 (human): Y90‑p, TYROBP (mouse): Y92‑p, TYROBP (rat): Y92‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y53-p - Vimentin (human)
Modsite: PstsrsLyAssPGGV SwissProt Entrez-Gene
Orthologous residues
Vimentin (human): Y53‑p, Vimentin (mouse): Y53‑p, Vimentin (rat): Y53‑p, Vimentin (rabbit): F53‑p, Vimentin (hamster): Y52‑p, Vimentin (cow): Y53‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y61-p - Vimentin (human)
Modsite: AssPGGVyAtrssAV SwissProt Entrez-Gene
Orthologous residues
Vimentin (human): Y61‑p, Vimentin (mouse): Y61‑p, Vimentin (rat): Y61‑p, Vimentin (rabbit): Y61‑p, Vimentin (hamster): Y60‑p, Vimentin (cow): Y61‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y426-p - Yes (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Yes (human): Y426‑p, Yes (mouse): Y424‑p, Yes (rat): Y424‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, chronic myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human