Curated Information
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Home > Curated Information Page > Cst Curation Set #1275
Gu T (2006) CST Curation Set: 1275; Year: 2006; Biosample/Treatment: bone marrow, myeloid/-; Disease: acute myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
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Y972-p - BCOR (human)
Modsite: RIANSAGyVGDRFKC SwissProt Entrez-Gene
Orthologous residues
BCOR (human): Y972‑p, BCoR iso2 (human): Y972‑p, BCOR (mouse): Y977‑p, BCoR iso2 (mouse): Y977‑p, BCoR iso3 (mouse): Y977‑p, BCoR iso4 (mouse): Y977‑p, BCOR (rat): Y975‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y15-p - CDK1 (human)
Modsite: EkIGEGtyGVVykGR SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): Y15‑p, CDK1 iso2 (human): Y15‑p, CDK1 (mouse): Y15‑p, CDK1 (rat): Y15‑p, CDK1 (chicken): Y15‑p, CDK1 (fruit fly): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y19-p - CDK1 (human)
Modsite: EGtyGVVykGRHkTT SwissProt Entrez-Gene
Orthologous residues
CDK1 (human): Y19‑p, CDK1 iso2 (human): Y19‑p, CDK1 (mouse): Y19‑p, CDK1 (rat): Y19‑p, CDK1 (chicken): Y19‑p, CDK1 (fruit fly): Y19‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y15-p - CDK2 (human)
Modsite: EkIGEGtyGVVykAR SwissProt Entrez-Gene
Orthologous residues
CDK2 (human): Y15‑p, CDK2 iso2 (human): Y15‑p, CDK2 (mouse): Y15‑p, CDK2 (rat): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y19-p - CDK2 (human)
Modsite: EGtyGVVykARNkLT SwissProt Entrez-Gene
Orthologous residues
CDK2 (human): Y19‑p, CDK2 iso2 (human): Y19‑p, CDK2 (mouse): Y19‑p, CDK2 (rat): Y19‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y15-p - CDK3 (human)
Modsite: EkIGEGtyGVVyKAK SwissProt Entrez-Gene
Orthologous residues
CDK3 (human): Y15‑p, CDK3 (mouse): Y15‑p, CDK3 (cow): Y15‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y19-p - CDK3 (human)
Modsite: EGtyGVVyKAKNRET SwissProt Entrez-Gene
Orthologous residues
CDK3 (human): Y19‑p, CDK3 (mouse): Y19‑p, CDK3 (cow): Y19‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y89-p - Cofilin-1 (human)
Modsite: yALyDAtyEtkEskk SwissProt Entrez-Gene
Orthologous residues
Cofilin‑1 (human): Y89‑p, Cofilin‑1 (mouse): Y89‑p, Cofilin‑1 (rat): Y89‑p, Cofilin‑1 (pig): Y89‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y89-p - Cofilin-2 (human)
Modsite: yALyDAtyEtkEskk SwissProt Entrez-Gene
Orthologous residues
Cofilin‑2 (human): Y89‑p, Cofilin‑2 (mouse): Y89‑p, Cofilin‑2 (rat): Y89‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y321-p - DYRK1A (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1A (human): Y321‑p, DYRK1A iso2 (human): Y312‑p, DYRK1A iso4 (human): Y321‑p, DYRK1A (mouse): Y321‑p, DYRK1A (rat): Y321‑p, DYRK1A (rabbit):
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y273-p - DYRK1B (human)
Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene
Orthologous residues
DYRK1B (human): Y273‑p, DYRK1B iso2 (human): Y273‑p, DYRK1B (mouse): Y273‑p, DYRK1B (rat): Y273‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y204-p - ERK1 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK1 (human): Y204‑p, ERK1 iso2 (human): Y204‑p, ERK1 iso3 (human): Y204‑p, ERK1 (mouse): Y205‑p, ERK1 (rat): Y205‑p, ERK1 (hamster): Y194‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y187-p - ERK2 (human)
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene
Orthologous residues
ERK2 (human): Y187‑p, ERK2 (mouse): Y185‑p, ERK2 (rat): Y185‑p, ERK2 (chicken): Y195‑p, ERK2 (cow): Y187‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y352-p - FAM46A (human)
Modsite: VGLEDRKyEyLMTLH SwissProt Entrez-Gene
Orthologous residues
FAM46A (human): Y352‑p, FAM46A iso2 (human): Y371‑p, FAM46A (rat): Y356‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y354-p - FAM46A (human)
Modsite: LEDRKyEyLMTLHGV SwissProt Entrez-Gene
Orthologous residues
FAM46A (human): Y354‑p, FAM46A iso2 (human): Y373‑p, FAM46A (rat): Y358‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y420-p - Fyn (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Fyn (human): Y420‑p, Fyn iso2 (human): Y417‑p, Fyn iso3 (human): Y365‑p, Fyn (mouse): Y420‑p, Fyn (rat): Y420‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y1105-p - GRF-1 (human)
Modsite: RNEEENIysVPHDst SwissProt Entrez-Gene
Orthologous residues
GRF‑1 (human): Y1105‑p, GRF‑1 (mouse): Y1105‑p, GRF‑1 (rat): Y1105‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y279-p - GSK3A (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3A (human): Y279‑p, GSK3A (mouse): Y279‑p, GSK3A (rat): Y279‑p, GSK3A (cow): Y279‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y216-p - GSK3B (human)
Modsite: RGEPNVsyICsRyyR SwissProt Entrez-Gene
Orthologous residues
GSK3B (human): Y216‑p, GSK3B iso2 (human): Y216‑p, GSK3B (mouse): Y216‑p, GSK3B (rat): Y216‑p, GSK3B (rabbit): Y216‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y352-p - HIPK1 (human)
Modsite: SkAVCstyLQsRYYR SwissProt Entrez-Gene
Orthologous residues
HIPK1 (human): Y352‑p, HIPK1 iso2 (human): Y352‑p, HIPK1 iso4 (human): , HIPK1 (mouse): Y352‑p, HIPK1 (rat): Y352‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y361-p - HIPK2 (human)
Modsite: SkAVCstyLQsRYyR SwissProt Entrez-Gene
Orthologous residues
HIPK2 (human): Y361‑p, HIPK2 (mouse): Y361‑p, HIPK2 (rat): Y361‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y359-p - HIPK3 (human)
Modsite: SkTVCstyLQsRYYR SwissProt Entrez-Gene
Orthologous residues
HIPK3 (human): Y359‑p, HIPK3 iso2 (human): Y359‑p, HIPK3 (mouse): Y359‑p, HIPK3 (rat): Y359‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y653-p - IRS2 (human)
Modsite: NLGADDGyMPMtPGA SwissProt Entrez-Gene
Orthologous residues
IRS2 (human): Y653‑p, IRS2 (mouse): Y649‑p, IRS2 (rat): Y650‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y675-p - IRS2 (human)
Modsite: GSCRsDDyMPMsPAs SwissProt Entrez-Gene
Orthologous residues
IRS2 (human): Y675‑p, IRS2 (mouse): Y671‑p, IRS2 (rat): Y672‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y823-p - IRS2 (human)
Modsite: CGGDsDQyVLMssPV SwissProt Entrez-Gene
Orthologous residues
IRS2 (human): Y823‑p, IRS2 (mouse): Y814‑p, IRS2 (rat): Y817‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y394-p - Lck (human)
Modsite: RLIEDNEytAREGAk SwissProt Entrez-Gene
Orthologous residues
Lck (human): Y394‑p, Lck iso3 (human): Y424‑p, Lck (mouse): Y394‑p, Lck (rat): Y394‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y182-p - P38A (human)
Modsite: tDDEMtGyVAtRWYR SwissProt Entrez-Gene
Orthologous residues
P38A (human): Y182‑p, P38A iso2 (human): Y182‑p, P38A (mouse): Y182‑p, P38A iso3 (mouse): Y182‑p, P38A (rat): Y182‑p, P38A (salmonid): Y183‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y185-p - P38G (human)
Modsite: ADsEMtGyVVTRWYR SwissProt Entrez-Gene
Orthologous residues
P38G (human): Y185‑p, P38G (mouse): Y185‑p, P38G (rat): Y185‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y849-p - PRP4 (human)
Modsite: ADNDItPyLVsRFyR SwissProt Entrez-Gene
Orthologous residues
PRP4 (human): Y849‑p, PRP4 (mouse): Y849‑p, PRP4 (rat): Y849‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y427-p - SHC1 (human)
Modsite: ELFDDPsyVNVQNLD SwissProt Entrez-Gene
Orthologous residues
SHC1 (human): Y427‑p, SHC1 iso2 (human): Y317‑p, SHC1 iso3 (human): Y272‑p, SHC1 iso6 (human): Y428‑p, SHC1 iso7 (human): Y318‑p, SHC1 (mouse): Y423‑p, SHC1 iso2 (mouse): Y313‑p, SHC1 iso3 (mouse): Y268‑p, SHC1 (rat): Y423‑p, SHC1 iso2 (rat): Y313‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y626-p - SMC5 (human)
Modsite: yVVKTSFySNkVISS SwissProt Entrez-Gene
Orthologous residues
SMC5 (human): Y626‑p, SMC5 (mouse): Y626‑p, SMC5 (rat): Y588‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y419-p - Src (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Src (human): Y419‑p, Src iso2 (human): Y425‑p, Src (mouse): Y424‑p, Src iso2 (mouse): Y418‑p, Src (rat): Y419‑p, Src (chicken): Y416‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y73-p - SSBP1 (human)
Modsite: RsGDsEVyQLGDVsQ SwissProt Entrez-Gene
Orthologous residues
SSBP1 (human): Y73‑p, SSBP1 (mouse): Y73‑p, SSBP1 iso2 (mouse): Y73‑p, SSBP1 (rat): Y73‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y705-p - STAT3 (human)
Modsite: DPGsAAPyLktKFIC SwissProt Entrez-Gene
Orthologous residues
STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y694-p - STAT5A (human)
Modsite: LAkAVDGyVkPQIkQ SwissProt Entrez-Gene
Orthologous residues
STAT5A (human): Y694‑p, STAT5A (mouse): Y694‑p, STAT5A iso2 (mouse): , STAT5A (rat): Y694‑p, STAT5A (fruit fly): , STAT5A (sheep): Y694‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y699-p - STAT5B (human)
Modsite: tAkAVDGyVkPQIkQ SwissProt Entrez-Gene
Orthologous residues
STAT5B (human): Y699‑p, STAT5B (mouse): Y699‑p, STAT5B (rat): Y699‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y323-p - Syk (human)
Modsite: sTVsFNPyEPELAPW SwissProt Entrez-Gene
Orthologous residues
Syk (human): Y323‑p, Syk iso2 (human): Y300‑p, Syk (mouse): Y317‑p, Syk (rat): Y317‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y91-p - TYROBP (human)
Modsite: ITETEsPyQELQGQR SwissProt Entrez-Gene
Orthologous residues
TYROBP (human): Y91‑p, TYROBP iso2 (human): Y90‑p, TYROBP (mouse): Y92‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y53-p - Vimentin (human)
Modsite: PstsrsLyAssPGGV SwissProt Entrez-Gene
Orthologous residues
Vimentin (human): Y53‑p, Vimentin (mouse): Y53‑p, Vimentin (rat): Y53‑p, Vimentin (rabbit): F53‑p, Vimentin (hamster): Y52‑p, Vimentin (cow): Y53‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y61-p - Vimentin (human)
Modsite: AssPGGVyAtrssAV SwissProt Entrez-Gene
Orthologous residues
Vimentin (human): Y61‑p, Vimentin (mouse): Y61‑p, Vimentin (rat): Y61‑p, Vimentin (rabbit): Y61‑p, Vimentin (hamster): Y60‑p, Vimentin (cow): Y61‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y426-p - Yes (human)
Modsite: RLIEDNEytARQGAk SwissProt Entrez-Gene
Orthologous residues
Yes (human): Y426‑p, Yes (mouse): Y424‑p, Yes (rat): Y424‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human

Y165-p - ZNF334 (human)
Modsite: NRKIPDGysGFGKHE SwissProt Entrez-Gene
Orthologous residues
ZNF334 (human): Y165‑p, ZNF334 (mouse): Q162‑p
Characterization
Methods used to characterize site in vivo mass spectrometry
Disease tissue studied:  leukemia, acute myelogenous leukemia
Relevant cell lines - cell types - tissues:  myeloid-bone marrow
Cellular systems studied:  cell lines
Species studied:  human