Curated Information
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus®
Powered by Cell Signaling Technology
Home > Curated Information Page > PubMed Id: 19796633
Morimura T, Ogawa M (2009) Relative importance of the tyrosine phosphorylation sites of Disabled-1 to the transmission of Reelin signaling. Brain Res 1304, 26-37 19796633
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.
Click on the protein name to open the protein page, and on the RSD number to open the site page.
Download

Y185-p - DAB1 (mouse)
Modsite: KQCEQAVyQTILEED SwissProt Entrez-Gene
Orthologous residues
DAB1 (human): Y185‑p, DAB1 (mouse): Y185‑p, DAB1 iso2 (mouse): Y185‑p, DAB1 iso3 (mouse): Y185‑p, DAB1 (rat): Y185‑p, DAB1 (pig): Y185‑p, DAB1 iso1 (pig): Y185‑p, DAB1 (chicken): Y185‑p, DAB1 iso2 (chicken): Y185‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  'brain, cerebral cortex'
Cellular systems studied:  tissue
Species studied:  mouse
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
reelin increase
Downstream Regulation
Effect of modification (function):  intracellular localization
Effect of modification (process):  cell motility, altered

Y198-p - DAB1 (mouse)
Modsite: EDVEDPVyQyIVFEA SwissProt Entrez-Gene
Orthologous residues
DAB1 (human): Y198‑p, DAB1 (mouse): Y198‑p, DAB1 iso2 (mouse): Y198‑p, DAB1 iso3 (mouse): Y198‑p, DAB1 (rat): Y198‑p, DAB1 (pig): Y198‑p, DAB1 iso1 (pig): , DAB1 (chicken): Y198‑p, DAB1 iso2 (chicken):
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  'brain, cerebral cortex'
Cellular systems studied:  tissue
Species studied:  mouse
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
reelin increase
Downstream Regulation
Effect of modification (function):  intracellular localization
Effect of modification (process):  cell motility, altered

Y220-p - DAB1 (mouse)
Modsite: PETEENIyQVPTSQK SwissProt Entrez-Gene
Orthologous residues
DAB1 (human): Y220‑p, DAB1 (mouse): Y220‑p, DAB1 iso2 (mouse): Y220‑p, DAB1 iso3 (mouse): Y220‑p, DAB1 (rat): Y220‑p, DAB1 (pig): Y220‑p, DAB1 iso1 (pig): , DAB1 (chicken): Y220‑p, DAB1 iso2 (chicken):
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  'brain, cerebral cortex'
Cellular systems studied:  tissue
Species studied:  mouse
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
reelin increase
Downstream Regulation
Effect of modification (function):  intracellular localization
Effect of modification (process):  cell motility, altered

Y232-p - DAB1 (mouse)
Modsite: SQKKEGVyDVPKSQP SwissProt Entrez-Gene
Orthologous residues
DAB1 (human): Y232‑p, DAB1 (mouse): Y232‑p, DAB1 iso2 (mouse): Y232‑p, DAB1 iso3 (mouse): Y232‑p, DAB1 (rat): Y232‑p, DAB1 (pig): Y232‑p, DAB1 iso1 (pig): Y197‑p, DAB1 (chicken): Y232‑p, DAB1 iso2 (chicken): Y197‑p
Characterization
Methods used to characterize site in vivo mutation of modification site
Relevant cell lines - cell types - tissues:  'brain, cerebral cortex'
Cellular systems studied:  tissue
Species studied:  mouse
Upstream Regulation
Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
reelin increase
Downstream Regulation
Effect of modification (function):  intracellular localization
Effect of modification (process):  cell motility, altered