Toska K, et al. (2002) Regulation of tyrosine hydroxylase by stress-activated protein kinases. J Neurochem 83, 775-83 12421349

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

Download

S19-p - TH iso3 (human) ▲

Modsite: KGFRRAVsELDAKQA SwissProt Entrez-Gene Orthologous residues TH (human): S19‑p, TH iso2 (human): S19‑p, TH iso3 (human): S19‑p, TH iso4 (human): S19‑p, TH (mouse): S19‑p, TH (rat): S19‑p, TH (cow): S19‑p Characterization Enzymes shown to modify site in vitro:  Type Enzyme KINASE MAPKAPK2 (human) KINASE MAPKAPK5 (human) Downstream Regulation Effect of modification (function):  molecular association, regulation Modification regulates interactions with:  Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays 14-3-3 zeta (sheep) Induces sequence-specific competitor, in vitro

S31-p - TH iso3 (human) ▲
Modsite: KQAEAIMsPRFIGRR SwissProt Entrez-Gene Orthologous residues TH (human): S62‑p, TH iso2 (human): S58‑p, TH iso3 (human): S31‑p, TH iso4 (human): S35‑p, TH (mouse): S31‑p, TH (rat): S31‑p, TH (cow): S31‑p Characterization Enzymes shown to modify site in vitro:  Type Enzyme KINASE ERK2 (human)

S40-p - TH iso3 (human) ▲

Modsite: RFIGRRQsLIEDARK SwissProt Entrez-Gene Orthologous residues TH (human): S71‑p, TH iso2 (human): S67‑p, TH iso3 (human): S40‑p, TH iso4 (human): S44‑p, TH (mouse): S40‑p, TH (rat): S40‑p, TH (cow): S40‑p Characterization Enzymes shown to modify site in vitro:  Type Enzyme KINASE MAPKAPK2 (human) KINASE MSK1 (human) KINASE MAPKAPK5 (human) Downstream Regulation Effect of modification (function):  enzymatic activity, induced

S404-p - TH iso3 (human) ▲
Modsite: GELLHCLsEEPEIRA SwissProt Entrez-Gene Orthologous residues TH (human): S435‑p, TH iso2 (human): S431‑p, TH iso3 (human): S404‑p, TH iso4 (human): S408‑p, TH (mouse): S405‑p, TH (rat): S405‑p, TH (cow): S398‑p Characterization Enzymes shown to modify site in vitro:  Type Enzyme KINASE MAPKAPK5 (human) KINASE MAPKAPK2 (human)