Goss V (2005) CST Curation Set: 673; Year: 2005; Biosample/Treatment: cell line, SD1/-; Disease: acute lymphocytic leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

Click on the protein name to open the protein page, and on the RSD number to open the site page.

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Y185-p - Abl (human) ▲

Modsite: TAsDGKLyVsSESRF SwissProt Entrez-Gene Orthologous residues Abl (human): Y185‑p, Abl iso2 (human): Y204‑p, Abl (mouse): Y185‑p, Abl iso4 (mouse): Y204‑p, Abl (rat): Y185‑p, Abl iso2 (rat): Y204‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y226-p - Abl (human) ▲

Modsite: KRNKPtVyGVsPNyD SwissProt Entrez-Gene Orthologous residues Abl (human): Y226‑p, Abl iso2 (human): Y245‑p, Abl (mouse): Y226‑p, Abl iso4 (mouse): Y245‑p, Abl (rat): Y226‑p, Abl iso2 (rat): Y245‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y393-p - Abl (human) ▲

Modsite: RLMtGDtytAHAGAk SwissProt Entrez-Gene Orthologous residues Abl (human): Y393‑p, Abl iso2 (human): Y412‑p, Abl (mouse): Y393‑p, Abl iso4 (mouse): Y412‑p, Abl (rat): Y393‑p, Abl iso2 (rat): Y412‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y518-p - Ack (human) ▲

Modsite: GGVKkPtyDPVSEDQ SwissProt Entrez-Gene Orthologous residues Ack (human): Y518‑p, Ack iso3 (human): Y596‑p, Ack (mouse): Y533‑p, Ack iso2 (mouse): Y518‑p, Ack (rat): Y518‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y859-p - Ack (human) ▲

Modsite: KKVsstHyyLLPERP SwissProt Entrez-Gene Orthologous residues Ack (human): Y859‑p, Ack iso3 (human): Y937‑p, Ack (mouse): Y874‑p, Ack iso2 (mouse): Y859‑p, Ack (rat): Y859‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y860-p - Ack (human) ▲

Modsite: KVsstHyyLLPERPs SwissProt Entrez-Gene Orthologous residues Ack (human): Y860‑p, Ack iso3 (human): Y938‑p, Ack (mouse): Y875‑p, Ack iso2 (mouse): Y860‑p, Ack (rat): Y860‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y294-p - ACTB (human) ▲

Modsite: VDIRkDLyANtVLsG SwissProt Entrez-Gene Orthologous residues ACTB (human): Y294‑p, ACTB (mouse): Y294‑p, ACTB (rat): Y294‑p, ACTB (cow): Y294‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y294-p - ACTG1 (human) ▲

Modsite: VDIRkDLyANtVLsG SwissProt Entrez-Gene Orthologous residues ACTG1 (human): Y294‑p, ACTG1 (mouse): Y294‑p, ACTG1 (rat): Y294‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y439-p - Arg (human) ▲

Modsite: RLMtGDtytAHAGAk SwissProt Entrez-Gene Orthologous residues Arg (human): Y439‑p, Arg iso2 (human): Y403‑p, Arg iso4 (human): Y404‑p, Arg iso6 (human): Y418‑p, Arg iso10 (human): Y424‑p, Arg (mouse): Y439‑p, Arg (rat): Y437‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y28-p - ARHGAP27 iso5 (human) ▲
Modsite: DDPPEPVyANIERQP SwissProt Entrez-Gene Orthologous residues ARHGAP27 (human): Y228‑p, ARHGAP27 iso5 (human): Y28‑p, ARHGAP27 (mouse): Y227‑p, ARHGAP27 iso2 (mouse): Y28‑p, ARHGAP27 iso3 (mouse): ‑, ARHGAP27 (rat): Y227‑p

Y174-p - BCHE (human) ▲
Modsite: VIVVSMNyRVGALGF SwissProt Entrez-Gene Orthologous residues BCHE (human): Y174‑p, BCHE (mouse): Y175‑p, BCHE (rat): Y169‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y177-p - Bcr (human) ▲

Modsite: ADAEKPFyVNVEFHH SwissProt Entrez-Gene Orthologous residues Bcr (human): Y177‑p, Bcr iso2 (human): Y177‑p, Bcr (mouse): Y178‑p, Bcr (rat): Y178‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y674-p - CBL (human) ▲
Modsite: sssANAIysLAARPL SwissProt Entrez-Gene Orthologous residues CBL (human): Y674‑p, CBL (mouse): Y672‑p, CBL (rat): Y673‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y700-p - CBL (human) ▲
Modsite: EGEEDtEyMtPssRP SwissProt Entrez-Gene Orthologous residues CBL (human): Y700‑p, CBL (mouse): Y698‑p, CBL (rat): Y699‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y665-p - Cbl-b (human) ▲

Modsite: GHLGsEEyDVPPRLs SwissProt Entrez-Gene Orthologous residues Cbl‑b (human): Y665‑p, Cbl‑b iso2 (human): Y665‑p, Cbl‑b (mouse): Y664‑p, Cbl‑b (rat): Y664‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y531-p - CD19 (human) ▲

Modsite: HEEDADsyENMDNPD SwissProt Entrez-Gene Orthologous residues CD19 (human): Y531‑p, CD19 iso2 (human): Y532‑p, CD19 (mouse): Y522‑p, CD19 (rat): Y522‑p, CD19 (rabbit): Y518‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y548-p - CD2AP (human) ▲
Modsite: ysPkPsVyLstPssA SwissProt Entrez-Gene Orthologous residues CD2AP (human): Y548‑p, CD2AP (mouse): ‑, CD2AP (rat): ‑ Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y15-p - CDK1 (human) ▲

Modsite: EkIGEGtyGVVykGR SwissProt Entrez-Gene Orthologous residues CDK1 (human): Y15‑p, CDK1 iso2 (human): Y15‑p, CDK1 (mouse): Y15‑p, CDK1 (rat): Y15‑p, CDK1 (chicken): Y15‑p, CDK1 (fruit fly): Y15‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y19-p - CDK1 (human) ▲

Modsite: EGtyGVVykGRHkTT SwissProt Entrez-Gene Orthologous residues CDK1 (human): Y19‑p, CDK1 iso2 (human): Y19‑p, CDK1 (mouse): Y19‑p, CDK1 (rat): Y19‑p, CDK1 (chicken): Y19‑p, CDK1 (fruit fly): Y19‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y15-p - CDK2 (human) ▲

Modsite: EkIGEGtyGVVykAR SwissProt Entrez-Gene Orthologous residues CDK2 (human): Y15‑p, CDK2 iso2 (human): Y15‑p, CDK2 (mouse): Y15‑p, CDK2 (rat): Y15‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y19-p - CDK2 (human) ▲

Modsite: EGtyGVVykARNkLT SwissProt Entrez-Gene Orthologous residues CDK2 (human): Y19‑p, CDK2 iso2 (human): Y19‑p, CDK2 (mouse): Y19‑p, CDK2 (rat): Y19‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y15-p - CDK3 (human) ▲
Modsite: EkIGEGtyGVVyKAK SwissProt Entrez-Gene Orthologous residues CDK3 (human): Y15‑p, CDK3 (mouse): Y15‑p, CDK3 (cow): Y15‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y19-p - CDK3 (human) ▲
Modsite: EGtyGVVyKAKNRET SwissProt Entrez-Gene Orthologous residues CDK3 (human): Y19‑p, CDK3 (mouse): Y19‑p, CDK3 (cow): Y19‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y77-p - CENTD1 (human) ▲

Modsite: KMQDIPIyANVHKTK SwissProt Entrez-Gene Orthologous residues CENTD1 (human): Y77‑p, CENTD1 (mouse): Y77‑p, CENTD1 (rat): Y77‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y473-p - CENTD1 (human) ▲

Modsite: SSQAISPyACFyGAS SwissProt Entrez-Gene Orthologous residues CENTD1 (human): Y473‑p, CENTD1 (mouse): Y471‑p, CENTD1 (rat): Y468‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y140-p - Cofilin-1 (human) ▲

Modsite: HELQANCyEEVkDRC SwissProt Entrez-Gene Orthologous residues Cofilin‑1 (human): Y140‑p, Cofilin‑1 (mouse): Y140‑p, Cofilin‑1 (rat): Y140‑p, Cofilin‑1 (pig): Y140‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y315-p - DOK1 (human) ▲

Modsite: CPsQDsLysDPLDST SwissProt Entrez-Gene Orthologous residues DOK1 (human): Y315‑p, DOK1 iso3 (human): Y176‑p, DOK1 (mouse): Y314‑p, DOK1 (rat): Y314‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y362-p - DOK1 (human) ▲

Modsite: DPKEDPIyDEPEGLA SwissProt Entrez-Gene Orthologous residues DOK1 (human): Y362‑p, DOK1 iso3 (human): Y223‑p, DOK1 (mouse): Y361‑p, DOK1 (rat): Y361‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y398-p - DOK1 (human) ▲

Modsite: ARVkEEGyELPyNPA SwissProt Entrez-Gene Orthologous residues DOK1 (human): Y398‑p, DOK1 iso3 (human): Y259‑p, DOK1 (mouse): Y397‑p, DOK1 (rat): Y397‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y409-p - DOK1 (human) ▲

Modsite: yNPAtDDyAVPPPRS SwissProt Entrez-Gene Orthologous residues DOK1 (human): Y409‑p, DOK1 iso3 (human): Y270‑p, DOK1 (mouse): Y408‑p, DOK1 (rat): Y408‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y449-p - DOK1 (human) ▲

Modsite: KsHNsALysQVQKSG SwissProt Entrez-Gene Orthologous residues DOK1 (human): Y449‑p, DOK1 iso3 (human): Y310‑p, DOK1 (mouse): Y450‑p, DOK1 (rat): Y448‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y299-p - DOK2 (human) ▲
Modsite: PRGQEGEyAVPFDAV SwissProt Entrez-Gene Orthologous residues DOK2 (human): Y299‑p, DOK2 (mouse): Y304‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y321-p - DYRK1A (human) ▲

Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene Orthologous residues DYRK1A (human): Y321‑p, DYRK1A iso2 (human): Y312‑p, DYRK1A iso4 (human): Y321‑p, DYRK1A (mouse): Y321‑p, DYRK1A (rat): Y321‑p, DYRK1A (rabbit): ‑ Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y273-p - DYRK1B (human) ▲

Modsite: LGQRIyQyIQsRFYR SwissProt Entrez-Gene Orthologous residues DYRK1B (human): Y273‑p, DYRK1B iso2 (human): Y273‑p, DYRK1B (mouse): Y273‑p, DYRK1B (rat): Y273‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y29-p - EEF1A1 (human) ▲

Modsite: tttGHLIykCGGIDk SwissProt Entrez-Gene Orthologous residues EEF1A1 (human): Y29‑p, EEF1A1 (mouse): Y29‑p, EEF1A1 (rat): Y29‑p, EEF1A1 (rabbit): Y29‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y29-p - EEF1A2 (human) ▲

Modsite: tttGHLIykCGGIDk SwissProt Entrez-Gene Orthologous residues EEF1A2 (human): Y29‑p, EEF1A2 (mouse): Y29‑p, EEF1A2 (rat): Y29‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y44-p - ENO1 (human) ▲

Modsite: sGAstGIyEALELrD SwissProt Entrez-Gene Orthologous residues ENO1 (human): Y44‑p, ENO1 (mouse): Y44‑p, ENO1 (rat): Y44‑p, ENO1 (chicken): Y44‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y44-p - ENO2 (human) ▲
Modsite: sGAstGIyEALELrD SwissProt Entrez-Gene Orthologous residues ENO2 (human): Y44‑p, ENO2 (mouse): Y44‑p, ENO2 (rat): Y44‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y44-p - ENO3 (human) ▲

Modsite: sGAstGIyEALELrD SwissProt Entrez-Gene Orthologous residues ENO3 (human): Y44‑p, ENO3 iso100 (human): Y44‑p, ENO3 (mouse): Y44‑p, ENO3 (rat): Y44‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y204-p - ERK1 (human) ▲

Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene Orthologous residues ERK1 (human): Y204‑p, ERK1 iso2 (human): Y204‑p, ERK1 iso3 (human): Y204‑p, ERK1 (mouse): Y205‑p, ERK1 (rat): Y205‑p, ERK1 (hamster): Y194‑p Characterization Methods used to characterize site in vivo:  mass spectrometry Disease tissue studied:  leukemia, acute lymphocytic leukemia Relevant cell lines - cell types - tissues:  SD1 (lymphoblastoid) Cellular systems studied:  cell lines Species studied:  human

Y187-p - ERK2 (human) ▲
Modsite: HtGFLtEyVAtRWyr SwissProt Entrez-Gene Orthologous residues ERK2 (human): Y187‑p, ERK2 (mouse): Y185‑p, ERK2 (rat): Y1