Site Group Page (References Reporting Low Throughput Detection Method)
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Site Group Page (References Reporting Low Throughput Detection Method)
 

Site Information
IkB-alpha (human) Y42-p DSMKDEEyEQMVKEL 1, 2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
IkB-alpha (mouse) Y42-p DSMKDEEyEQMVKEL
IkB-alpha (rat) Y42-p DSMKDEDyEQMVKEL 4

References

1

Culver C, et al. (2010) Mechanism of Hypoxia-Induced NF-{kappa}B. Mol Cell Biol 30, 4901-21
20696840   Curated Info

2

Zhong D, et al. (2008) LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins. Cancer Res 68, 7270-7
18794113   Curated Info

3

Sethi G, Ahn KS, Chaturvedi MM, Aggarwal BB (2007) Epidermal growth factor (EGF) activates nuclear factor-kappaB through IkappaBalpha kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IkappaBalpha. Oncogene 26, 7324-32
17533369   Curated Info

4

Azoitei N, Wirth T, Baumann B (2005) Activation of the IkappaB kinase complex is sufficient for neuronal differentiation of PC12 cells. J Neurochem 93, 1487-501
15935065   Curated Info

5

Waris G, et al. (2003) Hepatitis C virus NS5A and subgenomic replicon activate NF-kappaB via tyrosine phosphorylation of IkappaBalpha and its degradation by calpain protease. J Biol Chem 278, 40778-87
12909638   Curated Info

6

Fan C, Yang J, Engelhardt JF (2002) Temporal pattern of NFkappaB activation influences apoptotic cell fate in a stimuli-dependent fashion. J Cell Sci 115, 4843-53
12432072   Curated Info

7

Livolsi A, et al. (2001) Tyrosine phosphorylation-dependent activation of NF-kappa B. Requirement for p56 LCK and ZAP-70 protein tyrosine kinases. Eur J Biochem 268, 1508-15
11231305   Curated Info

8

Bui NT, Livolsi A, Peyron JF, Prehn JH (2001) Activation of nuclear factor kappaB and Bcl-x survival gene expression by nerve growth factor requires tyrosine phosphorylation of IkappaBalpha. J Cell Biol 152, 753-64
11266466   Curated Info

9

Schoonbroodt S, et al. (2000) Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress. J Immunol 164, 4292-300
10754328   Curated Info

10

Mukhopadhyay A, Manna SK, Aggarwal BB (2000) Pervanadate-induced nuclear factor-kappaB activation requires tyrosine phosphorylation and degradation of IkappaBalpha. Comparison with tumor necrosis factor-alpha. J Biol Chem 275, 8549-55
10722693   Curated Info

11

Abu-Amer Y, et al. (1998) Tumor necrosis factor-alpha activation of nuclear transcription factor-kappaB in marrow macrophages is mediated by c-Src tyrosine phosphorylation of Ikappa Balpha. J Biol Chem 273, 29417-23
9792645   Curated Info

12

DiDonato JA, et al. (1997) A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. Nature 388, 548-54
9252186   Curated Info

13

Imbert V, et al. (1996) Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha. Cell 86, 787-98
8797825   Curated Info

14

Brockman JA, et al. (1995) Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation. Mol Cell Biol 15, 2809-18
7739562   Curated Info

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