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Site Group Page (References Reporting Low Throughput Detection Method)
 

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RAF1 (human) Y340-p RGQRDSSyYWEIEAS 1, 2, 3, 5, 6, 8, 9, 10, 11, 12, 15, 16, 17, 19, 20, 21, 22, 23, 24
RAF1 (mouse) Y340-p RGQRDSSyYWEIEAS 7, 18
RAF1 (rat) Y340-p RGQRDSSyYWEIEAS 4, 12
RAF1 (chicken) Y340-p RGQRDSSyYWEIEAS 13, 14

References

1

Hibino K, Shibata T, Yanagida T, Sako Y (2011) Activation kinetics of RAF protein in the ternary complex of RAF, RAS-GTP, and kinase on the plasma membrane of living cells: single-molecule imaging analysis. J Biol Chem 286, 36460-8
21862573   Curated Info

2

Gringhuis SI, et al. (2010) HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells. Nat Immunol 11, 419-26
20364151   Curated Info

3

Dhillon AS, et al. (2009) The C-terminus of Raf-1 acts as a 14-3-3-dependent activation switch. Cell Signal 21, 1645-51
19595761   Curated Info

4

Tian HP, et al. (2009) Non-receptor tyrosine kinase Src is required for ischemia-stimulated neuronal cell proliferation via Raf/ERK/CREB activation in the dentate gyrus. BMC Neurosci 10, 139
19943942   Curated Info

5

Zang M, et al. (2008) Characterization of Ser338 phosphorylation for Raf-1 activation. J Biol Chem 283, 31429-37
18775988   Curated Info

6

Li M, et al. (2008) The SH3 domain of Lck modulates T-cell receptor-dependent activation of extracellular signal-regulated kinase through activation of Raf-1. Mol Cell Biol 28, 630-41
17998336   Curated Info

7

Kebache S, et al. (2007) Grb10 and active Raf-1 kinase promote Bad-dependent cell survival. J Biol Chem 282, 21873-83
17535812   Curated Info

8

Chen J, Siddiqui A (2007) Hepatitis B virus X protein stimulates the mitochondrial translocation of Raf-1 via oxidative stress. J Virol 81, 6757-60
17428866   Curated Info

9

Mei M, et al. (2006) Distribution, levels and phosphorylation of Raf-1 in Alzheimer's disease. J Neurochem 99, 1377-88
17064357   Curated Info

10

Jin S, Zhuo Y, Guo W, Field J (2005) p21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association. J Biol Chem 280, 24698-705
15849194   Curated Info

11

Baughn LB, Rosenberg N (2005) Disruption of the Shc/Grb2 complex during abelson virus transformation affects proliferation, but not apoptosis. J Virol 79, 2325-34
15681433   Curated Info

12

Hekman M, et al. (2004) Dynamic changes in C-Raf phosphorylation and 14-3-3 protein binding in response to growth factor stimulation: differential roles of 14-3-3 protein binding sites. J Biol Chem 279, 14074-86
14688280   Curated Info

13

Hood JD, et al. (2003) Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis. J Cell Biol 162, 933-43
12952943   Curated Info

14

Alavi A, et al. (2003) Role of Raf in vascular protection from distinct apoptotic stimuli. Science 301, 94-6
12843393   Curated Info

15

Tran NH, Frost JA (2003) Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition. J Biol Chem 278, 11221-6
12551923   Curated Info

16

Xiang X, et al. (2002) Phosphorylation of 338SSYY341 regulates specific interaction between Raf-1 and MEK1. J Biol Chem 277, 44996-5003
12244094   Curated Info

17

Zang M, et al. (2001) Microtubule integrity regulates Pak leading to Ras-independent activation of Raf-1. insights into mechanisms of Raf-1 activation. J Biol Chem 276, 25157-65
11274179   Curated Info

18

Hüser M, et al. (2001) MEK kinase activity is not necessary for Raf-1 function. EMBO J 20, 1940-51
11296227   Curated Info

19

Chiloeches A, Mason CS, Marais R (2001) S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3. Mol Cell Biol 21, 2423-34
11259591   Curated Info

20

Xing HR, Kolesnick R (2001) Kinase suppressor of Ras signals through Thr269 of c-Raf-1. J Biol Chem 276, 9733-41
11134016   Curated Info

21

Yip-Schneider MT, et al. (2000) Regulation of the Raf-1 kinase domain by phosphorylation and 14-3-3 association. Biochem J 351, 151-9
10998357   Curated Info

22

Laird AD, Morrison DK, Shalloway D (1999) Characterization of Raf-1 activation in mitosis. J Biol Chem 274, 4430-9
9933647   Curated Info

23

Cutler RE, Stephens RM, Saracino MR, Morrison DK (1998) Autoregulation of the Raf-1 serine/threonine kinase. Proc Natl Acad Sci U S A 95, 9214-9
9689060   Curated Info

24

Fabian JR, Daar IO, Morrison DK (1993) Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase. Mol Cell Biol 13, 7170-9
7692235   Curated Info

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