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H3 (human) S28-p ATkAArksAPATGGV Links 1, 3, 4, 5, 6, 7, 8, 10, 11, 15, 16, 17, 18, 19, 20, 21, 23, 25, 27, 28, 29, 30, 31, 35, 36, 38, 41, 42, 43, 46, 47, 49, 53, 54, 55
H3 (mouse) S28-p ATkAArksAPATGGV Links 2, 9, 12, 14, 24, 32, 33, 34, 37, 40, 45, 52
H3 iso2 (mouse) S28-p ATkAARKsAPATGGV Links 45
H3 iso3 (mouse) S28-p ATkAArksAPSTGGV Links 7, 26, 44, 45, 48, 50, 51, 56
H3 (rat) S28-p ATkAARksAPATGGV Links 13, 22
H3 (chicken) S28-p ATKAARksAPATGGV Links 39



Niu J, et al. (2016) Induction of miRNA-181a by genotoxic treatments promotes chemotherapeutic resistance and metastasis in breast cancer. Oncogene 35, 1302-13
26028030   Curated Info


Stützer A, et al. (2016) Modulations of DNA Contacts by Linker Histones and Post-translational Modifications Determine the Mobility and Modifiability of Nucleosomal H3 Tails. Mol Cell 61, 247-59
26778125   Curated Info


Kim SR, et al. (2016) H3S10 phosphorylation-mediated transcriptional regulation by Aurora kinase A. Biochem Biophys Res Commun 469, 22-8
26607113   Curated Info


Wurm S, et al. (2015) Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2. Genes Dev 29, 144-56
25547114   Curated Info


Pacaud R, et al. (2015) Histone H3 Phosphorylation in GBM: a New Rational to Guide the Use of Kinase Inhibitors in anti-GBM Therapy. Theranostics 5, 12-22
25553095   Curated Info


Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep 8, 1583-94
25159151   Curated Info


Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info


Yi T, et al. (2014) Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells. Proc Natl Acad Sci U S A 111, E2182-90
24782546   Curated Info


Hagemann S, et al. (2013) Loss of Survivin influences liver regeneration and is associated with impaired Aurora B function. Cell Death Differ 20, 834-44
23519077   Curated Info


Villagrasa P, et al. (2012) Akt2 interacts with Snail1 in the E-cadherin promoter. Oncogene 31, 4022-33
22158034   Curated Info


Huertas D, et al. (2012) Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin. Oncogene 31, 1408-18
21804608   Curated Info


Nogueira V, et al. (2012) Akt-dependent Skp2 mRNA translation is required for exiting contact inhibition, oncogenesis, and adipogenesis. EMBO J 31, 1134-46
22307088   Curated Info


James TT, Aroor AR, Lim RW, Shukla SD (2012) Histone H3 phosphorylation (Ser10, Ser28) and phosphoacetylation (K9S10) are differentially associated with gene expression in liver of rats treated in vivo with acute ethanol. J Pharmacol Exp Ther 340, 237-47
22025646   Curated Info


Zhang Q, et al. (2011) Phosphorylation of histone H3 serine 28 modulates RNA polymerase III-dependent transcription. Oncogene 30, 3943-52
21460852   Curated Info


Vagnarelli P, et al. (2011) Repo-Man coordinates chromosomal reorganization with nuclear envelope reassembly during mitotic exit. Dev Cell 21, 328-42
21820363   Curated Info


Qian J, et al. (2011) PP1/Repo-man dephosphorylates mitotic histone H3 at T3 and regulates chromosomal aurora B targeting. Curr Biol 21, 766-73
21514157   Curated Info


Lau PN, Cheung P (2011) Histone code pathway involving H3 S28 phosphorylation and K27 acetylation activates transcription and antagonizes polycomb silencing. Proc Natl Acad Sci U S A 108, 2801-6
21282660   Curated Info


Santamaria A, et al. (2011) The Plk1-dependent phosphoproteome of the early mitotic spindle. Mol Cell Proteomics 10, M110.004457
20860994   Curated Info


Rigbolt KT, et al. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Sci Signal 4, rs3
21406692   Curated Info


Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5
21712546   Curated Info


Gehani SS, et al. (2010) Polycomb group protein displacement and gene activation through MSK-dependent H3K27me3S28 phosphorylation. Mol Cell 39, 886-900
20864036   Curated Info


Aroor AR, James TT, Jackson DE, Shukla SD (2010) Differential changes in MAP kinases, histone modifications, and liver injury in rats acutely treated with ethanol. Alcohol Clin Exp Res 34, 1543-51
20586759   Curated Info


Dulla K, et al. (2010) Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression. Mol Cell Proteomics 9, 1167-81
20097925   Curated Info


Drobic B, et al. (2010) Promoter chromatin remodeling of immediate-early genes is mediated through H3 phosphorylation at either serine 28 or 10 by the MSK1 multi-protein complex. Nucleic Acids Res 38, 3196-208
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Shimada M, Nakadai T, Fukuda A, Hisatake K (2010) cAMP-response element-binding protein (CREB) controls MSK1-mediated phosphorylation of histone H3 at the c-fos promoter in vitro. J Biol Chem 285, 9390-401
20089855   Curated Info


Zhang J, et al. (2010) Cortical neural precursors inhibit their own differentiation via N-cadherin maintenance of beta-catenin signaling. Dev Cell 18, 472-9
20230753   Curated Info


Lopez-Bonet E, et al. (2010) Serine 2481-autophosphorylation of mammalian target of rapamycin (mTOR) couples with chromosome condensation and segregation during mitosis: confocal microscopy characterization and immunohistochemical validation of PP-mTOR(Ser2481) as a novel high-contrast mitosis marker in breast cancer core biopsies. Int J Oncol 36, 107-15
19956839   Curated Info


Olsen JV, et al. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal 3, ra3
20068231   Curated Info


Tjeertes JV, Miller KM, Jackson SP (2009) Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. EMBO J 28, 1878-89
19407812   Curated Info


Winter S, Fischle W, Seiser C (2008) Modulation of 14-3-3 interaction with phosphorylated histone H3 by combinatorial modification patterns. Cell Cycle 7, 1336-42
18418070   Curated Info


McNulty DE, Annan RS (2008) Hydrophilic interaction chromatography reduces the complexity of the phosphoproteome and improves global phosphopeptide isolation and detection. Mol Cell Proteomics 7, 971-80
18212344   Curated Info


Swain JE, Ding J, Wu J, Smith GD (2008) Regulation of spindle and chromatin dynamics during early and late stages of oocyte maturation by aurora kinases. Mol Hum Reprod 14, 291-9
18353803   Curated Info


Kim HG, et al. (2008) Mitogen- and stress-activated kinase 1-mediated histone H3 phosphorylation is crucial for cell transformation. Cancer Res 68, 2538-47
18381464   Curated Info


Wang Q, et al. (2008) The spatial relationship between heterochromatin protein 1 alpha and histone modifications during mouse oocyte meiosis. Cell Cycle 7, 513-20
18239470   Curated Info


Bonenfant D, et al. (2007) Analysis of dynamic changes in post-translational modifications of human histones during cell cycle by mass spectrometry. Mol Cell Proteomics 6, 1917-32
17644761   Curated Info


Yu LR, et al. (2007) Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra. J Proteome Res 6, 4150-62
17924679   Curated Info


Swain JE, et al. (2007) Proper chromatin condensation and maintenance of histone H3 phosphorylation during mouse oocyte meiosis requires protein phosphatase activity. Biol Reprod 76, 628-38
17182892   Curated Info


Burkhart BA, Kennett SB, Archer TK (2007) Osmotic stress-dependent repression is mediated by histone H3 phosphorylation and chromatin structure. J Biol Chem 282, 4400-7
17158874   Curated Info


Sun JM, Chen HY, Espino PS, Davie JR (2007) Phosphorylated serine 28 of histone H3 is associated with destabilized nucleosomes in transcribed chromatin. Nucleic Acids Res 35, 6640-7
17913747   Curated Info


Vicent GP, et al. (2006) Induction of progesterone target genes requires activation of Erk and Msk kinases and phosphorylation of histone H3. Mol Cell 24, 367-81
17081988   Curated Info


Jelínková L, Kubelka M (2006) Neither Aurora B activity nor histone H3 phosphorylation is essential for chromosome condensation during meiotic maturation of porcine oocytes. Biol Reprod 74, 905-12
16452462   Curated Info


Mishra S, et al. (2006) Phosphorylation of histones by tissue transglutaminase. J Biol Chem 281, 5532-8
16407273   Curated Info


Thomas CE, Kelleher NL, Mizzen CA (2006) Mass spectrometric characterization of human histone H3: a bird's eye view. J Proteome Res 5, 240-7
16457588   Curated Info


Choi HS, et al. (2005) Phosphorylation of histone H3 at serine 10 is indispensable for neoplastic cell transformation. Cancer Res 65, 5818-27
15994958   Curated Info


Dunn KL, Davie JR (2005) Stimulation of the Ras-MAPK pathway leads to independent phosphorylation of histone H3 on serine 10 and 28. Oncogene 24, 3492-502
15735677   Curated Info


Choi HS, et al. (2005) Phosphorylation of Ser28 in histone H3 mediated by mixed lineage kinase-like mitogen-activated protein triple kinase alpha. J Biol Chem 280, 13545-53
15684425   Curated Info


Dai J, Sultan S, Taylor SS, Higgins JM (2005) The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment. Genes Dev 19, 472-88
15681610   Curated Info


Mecklenbräuker I, et al. (2004) Regulation of B-cell survival by BAFF-dependent PKCdelta-mediated nuclear signalling. Nature 431, 456-61
15361883   Curated Info


Wang D, Lippard SJ (2004) Cisplatin-induced post-translational modification of histones H3 and H4. J Biol Chem 279, 20622-5
15010460   Curated Info


Mateescu B, et al. (2004) Tethering of HP1 proteins to chromatin is relieved by phosphoacetylation of histone H3. EMBO Rep 5, 490-6
15105826   Curated Info


Zhong S, Goto H, Inagaki M, Dong Z (2003) Phosphorylation at serine 28 and acetylation at lysine 9 of histone H3 induced by trichostatin A. Oncogene 22, 5291-7
12917630   Curated Info


Soloaga A, et al. (2003) MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14. EMBO J 22, 2788-97
12773393   Curated Info


Kawajiri A, et al. (2003) Functional significance of the specific sites phosphorylated in desmin at cleavage furrow: Aurora-B may phosphorylate and regulate type III intermediate filaments during cytokinesis coordinatedly with Rho-kinase. Mol Biol Cell 14, 1489-500
12686604   Curated Info


Sugiyama K, et al. (2002) Aurora-B associated protein phosphatases as negative regulators of kinase activation. Oncogene 21, 3103-11
12082625   Curated Info


Zhong S, et al. (2001) Ultraviolet B-induced phosphorylation of histone H3 at serine 28 is mediated by MSK1. J Biol Chem 276, 33213-9
11441012   Curated Info


Zhong S, et al. (2001) MAP kinases mediate UVB-induced phosphorylation of histone H3 at serine 28. J Biol Chem 276, 12932-7
11278789   Curated Info

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