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Site Group Page (LTP records: those reporting < 100 non-redundant sites)
 

Site Information
APP (human) Y757-p SKMQQNGyENPTYKF Links 4, 5, 6
APP iso4 (human) Y682-p SKMQQNGyENPTYKF Links 2, 8, 10
APP iso8 (human) Y738-p SKMQQNGyENPTYKF Links 11
APP (mouse) Y757-p SKMQQNGyENPTYKF Links 3, 9
APP iso2 (mouse) Y682-p SKMQQNGyENPTYKF Links 1, 7

Records

1

Del Prete D, Rice RC, Rajadhyaksha AM, D'Adamio L (2016) Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration. J Biol Chem 291, 17209-27
27325702   Curated Info

2

Riese F, et al. (2013) Visualization and Quantification of APP Intracellular Domain-Mediated Nuclear Signaling by Bimolecular Fluorescence Complementation. PLoS One 8, e76094
24086696   Curated Info

3

Matrone C, et al. (2011) APP is phosphorylated by TrkA and regulates NGF/TrkA signaling. J Neurosci 31, 11756-61
21849536   Curated Info

4

Austin SA, Sens MA, Combs CK (2009) Amyloid precursor protein mediates a tyrosine kinase-dependent activation response in endothelial cells. J Neurosci 29, 14451-62
19923279   Curated Info

5

Tamayev R, Zhou D, D'Adamio L (2009) The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains. Mol Neurodegener 4, 28
19602287   Curated Info

6

Hoe HS, et al. (2008) Fyn modulation of Dab1 effects on amyloid precursor protein and ApoE receptor 2 processing. J Biol Chem 283, 6288-99
18089558   Curated Info

7

Zhou D, et al. (2004) Growth factor receptor-bound protein 2 interaction with the tyrosine-phosphorylated tail of amyloid beta precursor protein is mediated by its Src homology 2 domain. J Biol Chem 279, 25374-80
15054097   Curated Info

8

Tarr PE, et al. (2002) Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP. Biochem Biophys Res Commun 295, 324-9
12150951   Curated Info

9

Tarr PE, et al. (2002) Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc. J Biol Chem 277, 16798-804
11877420   Curated Info

10

Zambrano N, et al. (2001) The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene. J Biol Chem 276, 19787-92
11279131   Curated Info

11

Jacobsen JS, et al. (1994) The release of Alzheimer's disease beta amyloid peptide is reduced by phorbol treatment. J Biol Chem 269, 8376-82
8132561   Curated Info

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