Site Group Page (LTP records: Sites observed with LTP technologies)
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Site Group Page (LTP records: Sites observed with LTP technologies)

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APP (human) Y757-p SkMQQNGyENPtykF Links 4, 5, 6
APP iso4 (human) Y682-p SKMQQNGyENPTyKF Links 2, 8, 10
APP iso8 (human) Y738-p SKMQQNGyENPTyKF Links 11
APP (mouse) Y757-p SkMQQNGyENPTykF Links 3, 9
APP iso2 (mouse) Y682-p SkMQQNGyENPTykF Links 1, 7



Del Prete D, Rice RC, Rajadhyaksha AM, D'Adamio L (2016) Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration. J Biol Chem 291, 17209-27
27325702   Curated Info


Riese F, et al. (2013) Visualization and Quantification of APP Intracellular Domain-Mediated Nuclear Signaling by Bimolecular Fluorescence Complementation. PLoS One 8, e76094
24086696   Curated Info


Matrone C, et al. (2011) APP is phosphorylated by TrkA and regulates NGF/TrkA signaling. J Neurosci 31, 11756-61
21849536   Curated Info


Austin SA, Sens MA, Combs CK (2009) Amyloid precursor protein mediates a tyrosine kinase-dependent activation response in endothelial cells. J Neurosci 29, 14451-62
19923279   Curated Info


Tamayev R, Zhou D, D'Adamio L (2009) The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains. Mol Neurodegener 4, 28
19602287   Curated Info


Hoe HS, et al. (2008) Fyn modulation of Dab1 effects on amyloid precursor protein and ApoE receptor 2 processing. J Biol Chem 283, 6288-99
18089558   Curated Info


Zhou D, et al. (2004) Growth factor receptor-bound protein 2 interaction with the tyrosine-phosphorylated tail of amyloid beta precursor protein is mediated by its Src homology 2 domain. J Biol Chem 279, 25374-80
15054097   Curated Info


Tarr PE, et al. (2002) Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP. Biochem Biophys Res Commun 295, 324-9
12150951   Curated Info


Tarr PE, et al. (2002) Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc. J Biol Chem 277, 16798-804
11877420   Curated Info


Zambrano N, et al. (2001) The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene. J Biol Chem 276, 19787-92
11279131   Curated Info


Jacobsen JS, et al. (1994) The release of Alzheimer's disease beta amyloid peptide is reduced by phorbol treatment. J Biol Chem 269, 8376-82
8132561   Curated Info

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