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Moesin (human) T558-p LGRDKYKtLRQIRQG Links 1, 2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 16, 17, 18, 19, 21, 22, 23, 25, 27, 28, 30
Moesin (mouse) T558-p LGRDKYKtLRQIRQG Links 4, 13, 14, 17, 26, 29, 31
Moesin (rat) T558-p LGRDKYKtLRQIRQG Links 15, 20, 24

Records

1

Vitorino P, et al. (2015) MAP4K4 regulates integrin-FERM binding to control endothelial cell motility. Nature 519, 425-30
25799996   Curated Info

2

Madsen CD, et al. (2015) STRIPAK components determine mode of cancer cell migration and metastasis. Nat Cell Biol 17, 68-80
25531779   Curated Info

3

Ghaffari A, et al. (2014) A novel role for ezrin in breast cancer angio/lymphangiogenesis. Breast Cancer Res 16, 438
25231728   Curated Info

4

Cannon JL, et al. (2013) PKCθ regulates T cell motility via ezrin-radixin-moesin localization to the uropod. PLoS One 8, e78940
24250818   Curated Info

5

Luo Y, et al. (2012) Recognition of CD146 as an ERM-binding protein offers novel mechanisms for melanoma cell migration. Oncogene 31, 306-21
21725352   Curated Info

6

Wakayama Y, Miura K, Sabe H, Mochizuki N (2011) EphrinA1-EphA2 signal induces compaction and polarization of Madin-Darby canine kidney cells by inactivating Ezrin through negative regulation of RhoA. J Biol Chem 286, 44243-53
21979959   Curated Info

7

Heiska L, et al. (2011) Ezrin is key regulator of Src-induced malignant phenotype in three-dimensional environment. Oncogene 30, 4953-62
21666723   Curated Info

8

Adyshev DM, et al. (2011) Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement. Cell Signal 23, 2086-96
21864676   Curated Info

9

Harris SJ, et al. (2011) Evidence that the lipid phosphatase SHIP-1 regulates T lymphocyte morphology and motility. J Immunol 186, 4936-45
21402888   Curated Info

10

Shichi D, Arimura T, Ishikawa T, Kimura A (2010) Heart-specific small subunit of myosin light chain phosphatase activates rho-associated kinase and regulates phosphorylation of myosin phosphatase target subunit 1. J Biol Chem 285, 33680-90
20801872   Curated Info

11

Kahsai AW, Zhu S, Fenteany G (2010) G protein-coupled receptor kinase 2 activates radixin, regulating membrane protrusion and motility in epithelial cells. Biochim Biophys Acta 1803, 300-10
19913059   Curated Info

12

Wu B, Jiang P, Mu Y, Wilmouth RC (2009) Cancer Osaka thyroid (Cot) phosphorylates Polo-like kinase (PLK1) at Ser137 but not at Thr210. Biol Chem 390, 1271-7
19804365   Curated Info

13

Parisiadou L, et al. (2009) Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis. J Neurosci 29, 13971-80
19890007   Curated Info

14

Sawada N, et al. (2009) Cyclic GMP kinase and RhoA Ser188 phosphorylation integrate pro- and antifibrotic signals in blood vessels. Mol Cell Biol 29, 6018-32
19737918   Curated Info

15

Sanchez AM, et al. (2009) Rapid signaling of estrogen to WAVE1 and moesin controls neuronal spine formation via the actin cytoskeleton. Mol Endocrinol 23, 1193-202
19460862   Curated Info

16

Guo X, et al. (2009) ERM protein moesin is phosphorylated by advanced glycation end products and modulates endothelial permeability. Am J Physiol Heart Circ Physiol 297, H238-46
19395553   Curated Info

17

Belkina NV, et al. (2009) LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation. Proc Natl Acad Sci U S A 106, 4707-12
19255442   Curated Info

18

Covy JP, Giasson BI (2009) Identification of compounds that inhibit the kinase activity of leucine-rich repeat kinase 2. Biochem Biophys Res Commun 378, 473-7
19027715   Curated Info

19

Jaleel M, et al. (2007) LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity. Biochem J 405, 307-17
17447891   Curated Info

20

Baumgartner M, et al. (2006) The Nck-interacting kinase phosphorylates ERM proteins for formation of lamellipodium by growth factors. Proc Natl Acad Sci U S A 103, 13391-6
16938849   Curated Info

21

Simoncini T, et al. (2006) Estrogen receptor alpha interacts with Galpha13 to drive actin remodeling and endothelial cell migration via the RhoA/Rho kinase/moesin pathway. Mol Endocrinol 20, 1756-71
16601072   Curated Info

22

Jeon S, et al. (2005) Chloride conductance is required for the protein kinase A and Rac1-dependent phosphorylation of moesin at Thr-558 by KCl in PC12 cells. J Biol Chem 280, 12181-9
15634677   Curated Info

23

Yokoyama T, et al. (2005) Aurora-B and Rho-kinase/ROCK, the two cleavage furrow kinases, independently regulate the progression of cytokinesis: possible existence of a novel cleavage furrow kinase phosphorylates ezrin/radixin/moesin (ERM). Genes Cells 10, 127-37
15676024   Curated Info

24

Kim SJ, et al. (2004) AMPA, not NMDA, activates RhoA GTPases and subsequently phosphorylates moesin. Exp Mol Med 36, 98-102
15031678   Curated Info

25

Wang Q, Pfeiffer GR, Gaarde WA (2003) Activation of SRC tyrosine kinases in response to ICAM-1 ligation in pulmonary microvascular endothelial cells. J Biol Chem 278, 47731-43
14504278   Curated Info

26

Jeon S, et al. (2002) RhoA and Rho kinase-dependent phosphorylation of moesin at Thr-558 in hippocampal neuronal cells by glutamate. J Biol Chem 277, 16576-84
11867620   Curated Info

27

Kosako H, et al. (2000) Rho-kinase/ROCK is involved in cytokinesis through the phosphorylation of myosin light chain and not ezrin/radixin/moesin proteins at the cleavage furrow. Oncogene 19, 6059-64
11146558   Curated Info

28

Hishiya A, Ohnishi M, Tamura S, Nakamura F (1999) Protein phosphatase 2C inactivates F-actin binding of human platelet moesin. J Biol Chem 274, 26705-12
10480873   Curated Info

29

Oshiro N, Fukata Y, Kaibuchi K (1998) Phosphorylation of moesin by rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures. J Biol Chem 273, 34663-6
9856983   Curated Info

30

Pietromonaco SF, Simons PC, Altman A, Elias L (1998) Protein kinase C-theta phosphorylation of moesin in the actin-binding sequence. J Biol Chem 273, 7594-603
9516463   Curated Info

31

Matsui T, et al. (1998) Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association. J Cell Biol 140, 647-57
9456324   Curated Info

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