Ser105
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Phosphorylation Site Page:
Ser105 - tau iso3 (human)

Site Information
GDRSGYSsPGSPGTP    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: tau iso8 (human): S199, tau (rat): S510, tau (mouse): S491, tau iso5 (human): S199, tau (human): S516, tau iso7 (human): S170, tau iso7 (mouse): S148, tau iso3 (mouse): S188, tau (cow): S206, tau iso6 (human): S141, tau iso2 (human): S141
Blast this site against: NCBI  SwissProt  PDB 

In vivo Characterization
Methods used to characterize site in vivo: mutation of modification site (1)
Disease tissue studied: adrenal cancer (1), pheochromocytoma (1)
Relevant cell line - cell type - tissue: PC-12 (chromaffin) (1)

Controlled by
Treatments: okadaic acid (1)

Downstream Regulation
Effects of modification on tau iso3: molecular association, regulation (1)
Effects of modification on biological processes: cytoskeletal reorganization (1)


References

1

Maas T, Eidenmüller J, Brandt R (2000) Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments. J Biol Chem 275, 15733-40
10747907   Curated Info

Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.