Thr1207
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Phosphorylation Site Page:
Thr1207 - SCC-112 (mouse)

Site Information
PVRIISVtPVKNIDT    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: SCC‑112 (human): T1208, SCC‑112 (rat): T1207
Blast this site against: NCBI  SwissProt  PDB 

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (2, 3)
Relevant cell line - cell type - tissue: 32Dcl3 (myeloid) [FLT3 (mouse), transfection, chimera with human FLT3-ITD mutant (corresponding to wild type P36888 ~aa 525-695 ETILLNS...IFEYCC)] (3), MEF (fibroblast) [p53 (mouse), homozygous knockout] (2)




References

1

(2011) CST Curation Set: 12730; Year: 2011; Biosample: mouse neuroendocrine tumor; Disease: brain cancer; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-(s/t)P(phosphorylation)
Curated Info

2

Hsu PP, et al. (2011) The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-22
21659604   Curated Info

3

Choudhary C, et al. (2009) Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes. Mol Cell 36, 326-39
19854140   Curated Info

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