Ser741
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Phosphorylation Site Page:
Ser741 - Kit (human)

Site Information
TKADKRRsVRIGSYI    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: Kit (mouse): S743
Blast this site against: NCBI  SwissProt  PDB 

In vivo Characterization
Methods used to characterize site in vivo: [32P] bio-synthetic labeling (1), mutation of modification site (1), phosphoamino acid analysis (1)
Relevant cell line - cell type - tissue: PAE (endothelial) (1)

Controlled by
Kinases, in vitro: PKCA (human) (1)
Treatments: SCF (1)

Downstream Regulation
Effects of modification on Kit: enzymatic activity, inhibited (1), phosphorylation (1)


References

1

Blume-Jensen P, Wernstedt C, Heldin CH, Rönnstrand L (1995) Identification of the major phosphorylation sites for protein kinase C in kit/stem cell factor receptor in vitro and in intact cells. J Biol Chem 270, 14192-200
7539802   Curated Info

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