Lys328
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Acetylation Site Page:
Lys328 - ACTC1 (mouse)

Site Information
ALAPSTMkIKIIAPP    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: ACTC1 (human): K328, ACTC1 (rat): K328
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 7801863

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3)
Relevant cell line - cell type - tissue: colon (1), liver (1, 2), MEF (fibroblast) [HDAC6 (mouse), heterozygous knockout] (3)

Controlled by
Treatments: gut microbiota (1)



References

1

Simon GM, Cheng J, Gordon JI (2012) Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice. Proc Natl Acad Sci U S A 109, 11133-8
22733758   Curated Info

2

(2009) CST Curation Set: 7494; Year: 2009; Biosample/Treatment: tissue, liver/0.1% serum; Disease: -; SILAC: -; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-AcK Antibody Used to Purify Peptides prior to MS2: Acetylated-Lysine (Ac-K2-100) Rabbit mAb Cat#: 9814, PTMScan(R) Acetyl-Lys Motif (Ac-K) Immunoaffinity Beads Cat#: 1989
Curated Info

3

(2006) CST Curation Set: 1907; Year: 2006; Biosample/Treatment: cell line, MEF[HDAC6(heterozygous knockout)]/untreated; Disease: -; SILAC: -; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-AcK Antibody Used to Purify Peptides prior to MS2: Acetylated-Lysine (Ac-K2-100) Rabbit mAb Cat#: 9814, PTMScan(R) Acetyl-Lys Motif (Ac-K) Immunoaffinity Beads Cat#: 1989
Curated Info

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