Thr1727

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Phosphorylation Site Page:

Thr1727 - ITGB4 iso2 (human)

Site Information

GSLTRHVtQEFVSRT SwissProt Entrez-Gene

Predicted information: Scansite

Orthologous residues: ITGB4 (human): T1797, ITGB4 iso3 (mouse): T1781, ITGB4 (mouse): T1793, ITGB4 iso3 (human): T1780, ITGB4 (rat): T1782, ITGB4 iso2 (mouse): T1728

Blast this site against: NCBI SwissProt PDB

In vivo Characterization

Methods used to characterize site in vivo:	mass spectrometry (2)
Relevant cell line - cell type - tissue:	MKN-45 (gastric) (2)

	References

Frijns E, et al. (2012) Phosphorylation of threonine 1736 in the C-terminal tail of integrin β4 contributes to hemidesmosome disassembly. Mol Biol Cell 23, 1475-85
22357621 Curated Info

(2008) CST Curation Set: 4494; Year: 2008; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: normal & normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-RXX(s/t)(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info

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