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Phosphorylation Site Page:
Ser140 - Chk2 (human)

Site Information
TDKYRTYsKKHFRIF    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: Chk2 (rat): S143, Chk2 (mouse): S144, Chk2 iso12 (human): S140, Chk2 iso11 (human):
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 6339800

Controlled by
Kinases, in vitro: Chk2 (human) (1)

Downstream Regulation
Effects of modification on Chk2: enzymatic activity, induced (1), protein conformation (1)
Induce interaction with: PLK1 (human) (1)



Li J, et al. (2008) Chk2 oligomerization studied by phosphopeptide ligation: implications for regulation and phosphodependent interactions. J Biol Chem 283, 36019-30
18948271   Curated Info

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