Ser686

Javascript is not enabled on this browser. This site will not work properly without Javascript.

Phosphorylation Site Page:

Site Information

KKKLVINsGNGAVED SwissProt Entrez-Gene

Predicted information: Scansite

Orthologous residues: CD44 iso2 (mouse): G307, CD44 (rat): S447, CD44 (mouse): G722

Blast this site against: NCBI SwissProt PDB

In vivo Characterization

Methods used to characterize site in vivo:	mass spectrometry (2, 3, 4, 5, 6)
Disease tissue studied:	cervical cancer (3), cervical adenocarcinoma (3)
Relevant cell line - cell type - tissue:	GM00130 (B lymphocyte) (2), HeLa (cervical) (4, 6), HeLa S3 (cervical) (3), TERT20 ('stem, mesenchymal') (5)

Controlled by

Treatments:

ionizing radiation (2), nocodazole (3)

	References

1	Shiromizu T, et al. (2013) Identification of Missing Proteins in the neXtProt Database and Unregistered Phosphopeptides in the PhosphoSitePlus Database As Part of the Chromosome-Centric Human Proteome Project. J Proteome Res 23312004 Curated Info
2	Bennetzen MV, et al. (2010) Site-specific phosphorylation dynamics of the nuclear proteome during the DNA damage response. Mol Cell Proteomics 9, 1314-23 20164059 Curated Info
3	Olsen JV, et al. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal 3, ra3 20068231 Curated Info
4	Dephoure N, et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A 105, 10762-7 18669648 Curated Info
5	Thingholm TE, et al. (2008) TiO2-Based Phosphoproteomic Analysis of the Plasma Membrane and the Effects of Phosphatase Inhibitor Treatment. J Proteome Res 7, 3304-3313 18578522 Curated Info
6	Olsen JV, et al. (2006) Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 127, 635-48 17081983 Curated Info

Home \| Curator Login	With enhanced literature mining using Linguamatics I2E		Produced by 3rd Millennium \| Design by Digizyme
			©2003-2013 Cell Signaling Technology, Inc.