Ser1164
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Phosphorylation Site Page:
Ser1164 - MybBP1A (mouse)

Site Information
DIPSDTQsPVSTKRK    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: MybBP1A (human): S1163, MybBP1A (rat): S1166
Blast this site against: NCBI  SwissProt  PDB 

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3, 4, 6, 7, 8)
Relevant cell line - cell type - tissue: 32Dcl3 (myeloid) (6), 32Dcl3 (myeloid) [FLT3 (mouse), transfection, chimera with human FLT3-ITD mutant (corresponding to wild type P36888 ~aa 525-695 ETILLNS...IFEYCC)] (6), 3T3 (fibroblast) (8), Hepa 1-6 (epithelial) (7), liver (4), lung (4), MEF (fibroblast) (1, 3), MEF (fibroblast) [p53 (mouse), homozygous knockout] (2), MEF (fibroblast) [raptor (mouse), knockdown] (1), MEF (fibroblast) [rictor (mouse), knockdown] (1), MEF (fibroblast) [TSC2 (mouse), homozygous knockout] (3), pancreas (4), spleen (4), testis (4)

Controlled by
Regulatory protein: raptor (mouse) (1), rictor (mouse) (1)



References

1

Robitaille AM, et al. (2013) Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis. Science 339, 1320-3
23429704   Curated Info

2

Hsu PP, et al. (2011) The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-22
21659604   Curated Info

3

Yu Y, et al. (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332, 1322-6
21659605   Curated Info

4

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

5

(2009) CST Curation Set: 8607; Year: 2009; Biosample: embryonic stem cells (mouse)(PTEN); Disease: -; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-(s/t)P(phosphorylation)
Curated Info

6

Choudhary C, et al. (2009) Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes. Mol Cell 36, 326-39
19854140   Curated Info

7

Pan C, Gnad F, Olsen JV, Mann M (2008) Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors. Proteomics 8, 4534-46
18846507   Curated Info

8

Wang Z, Gucek M, Hart GW (2008) Cross-talk between GlcNAcylation and phosphorylation: site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc. Proc Natl Acad Sci U S A 105, 13793-8
18779572   Curated Info

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