Tyr877
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Phosphorylation Site Page:
Tyr877 - HER2 (human)

Site Information
LDIDETEyHADGGKV    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: HER2 (rat): Y879, HER2 (mouse): Y878, HER2 iso2 (human): Y267
Blast this site against: NCBI  SwissProt  PDB 
Available spectra:  4 CST

In vivo Characterization
Methods used to characterize site in vivo: immunoprecipitation (27), mass spectrometry (2, 3, 4, 5, 6, 7, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 25, 28, 29, 30, 31, 32, 35, 39, 40, 41, 42, 43, 44, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 103), mutation of modification site (45), phospho-antibody (21, 26, 27, 37, 38, 45, 61, 89, 102), western blotting (21, 26, 27, 37, 45, 61)
Disease tissue studied: bile-duct cancer (2), bladder cancer (68), breast cancer (21, 41, 42, 52, 53, 54, 55, 56, 57, 58, 59, 60, 63, 64, 65, 66, 69, 70, 71, 72, 73, 74, 77, 79, 80, 83, 84, 85, 86, 97), breast adenocarcinoma (85, 97), breast ductal carcinoma (55, 59, 60), breast cancer, triple negative (55, 71, 72), cervical cancer (27), colorectal cancer (4, 15), colorectal carcinoma (4, 15), esophageal cancer (31, 32, 91), esophageal carcinoma (31, 32), gastric cancer (5, 6, 7, 9, 10, 11, 12, 17, 18, 46, 47, 48, 49, 87), gastric carcinoma (5, 6, 7, 9, 10, 11, 12, 17, 18), kidney cancer (67), leukemia (28, 29, 30), chronic myelogenous leukemia (28, 29, 30), liver cancer (40), hepatocellular carcinoma (40), lung cancer (3, 13, 14, 16, 21, 26, 35, 38, 50, 51, 81, 92, 93, 94, 95, 96, 98, 100, 101), non-small cell lung cancer (3, 13, 14, 16, 26, 38, 50, 51, 92, 93, 94, 96, 98, 100), non-small cell lung adenocarcinoma (35, 50, 51, 81, 94), non-small cell squamous cell lung carcinoma (92, 100), lymphoma (75), Hodgkin's lymphoma (75), ovarian cancer (61, 88, 90), ovarian epithelial carcinoma (88, 90), prostate cancer (27), melanoma skin cancer (44)
Relevant cell line - cell type - tissue: 293T (epithelial) (45), 3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout] (89), 41M (ovarian) (61), 639L (renal) (67), A549 (pulmonary) (26), AGS (gastric) (87), AU565 (breast cell) (69, 70), BT-474 (breast cell) (21, 41, 89), C33-A (cervical) (27), CAL-85-1 (breast cell) (85), Calu-3 (pulmonary) (51, 95, 101), CAMA-1 (breast cell) (54), Caov-3 (ovarian) (61), EFM-19 (breast cell) (78), EFM-192A (breast cell) (79), EVSA-T (breast cell) (83), HCC1187 (breast cell) (55), HCC1419 (breast cell) (59, 60), HCC1569 (breast cell) (57, 58), HCC1599 (breast cell) (63, 64), HCC202 (breast cell) (52, 53), HCC38 (breast cell) (71, 72), HCC827 (pulmonary) (50, 51, 94), HCT116 (intestinal) (4, 15), HD-MyZ (myeloid) (75), HDQ-P1 (breast cell) (80), HepG2 (hepatic) (40), HMEC (endothelial) (76), HMEC 24H (endothelial) (76), IM95 (gastric) (47), JIMT-1 (breast cell) (77, 84), K562 (erythroid) (28, 29, 30), KPL-1 (breast cell) (86), Kyse30 (esophageal) (31), Kyse510 (esophageal) (91), Kyse70 (esophageal) (32), LNCaP (prostate cell) (27), MDA-MB231 (breast cell) (25), MDA-MB231 (breast cell) [Syk (human), transfection, Tet-reponsive Syk-inducible system] (25), MDA-MB361 (breast cell) (42), MKN-45 (gastric) (5, 6, 7, 9, 10, 11, 12, 17, 18), MKN-7 (gastric) (49), N87 (gastric) (99), NCI-H1650 (pulmonary) (13, 14, 16, 26, 103), NCI-H1666 (pulmonary) (50, 51, 93), NCI-H1703 (squamous) (43), NCI-H1734 (pulmonary) (50, 51), NCI-H1869 (squamous) (51, 92), NCI-H1975 (pulmonary) (26), NCI-H2170 (squamous) (51, 100), NCI-H292 (pulmonary) (21), NCI-H3255 (pulmonary) (3, 35, 50, 51, 96, 98), NCI-H460 (pulmonary) (38), NUGC-3 (gastric) (48), OCUM-1 (gastric) (46), OVCAR4 (ovarian) (61), OVCAR5 (ovarian) (61), OZ (bile-duct cell) [RAIG1 (human), knockdown] (2), PC9 (pulmonary) (82), PC9-IR (pulmonary) (81), PEO4 (ovarian) (61), PEO6 (ovarian) (61), Rat1 (fibroblast) (37), Schwann (45), SKBr3 (breast cell) (21, 97, 102), skin (44), SKOV-3 (ovarian) (61, 88, 90), SW780 (bladder cell) (68), UACC-812 (breast cell) (65, 66), UACC-893 (breast cell) (56), ZR-75-30 (breast cell) (73, 74)

Controlled by
Putative upstream kinases: HER2 (human) (89)
Putative upstream phosphatases: ACPP (human) (27)
Treatments: 2-deoxyglucose (38), AEE788 (26), anti-HER2 (102), EGF (26), erlotinib (26), estrogen (61), forskolin (45), heregulin (61), neuregulin (45), PD168393 (89), pertuzumab (61), tamoxifen (61), TGF-alpha (61)

Downstream Regulation
Effects of modification on biological processes: cell growth, altered (37)


References

1

Shiromizu T, et al. (2013) Identification of Missing Proteins in the neXtProt Database and Unregistered Phosphopeptides in the PhosphoSitePlus Database As Part of the Chromosome-Centric Human Proteome Project. J Proteome Res
23312004   Curated Info

2

(2012) CST Curation Set: 13502; Year: 2012; Biosample: OZ; Disease: bile-duct cancer; Treatment: GPRC5A knockdown; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

3

(2012) CST Curation Set: 13325; Year: 2012; Biosample: H3255; Disease: non-small cell lung cancer; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

4

(2012) CST Curation Set: 13333; Year: 2012; Biosample: HCT 116; Disease: colorectal carcinoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr
Curated Info

5

(2011) CST Curation Set: 12853; Year: 2011; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

6

(2011) CST Curation Set: 12855; Year: 2011; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

7

(2011) CST Curation Set: 12518; Year: 2011; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

8

(2011) CST Curation Set: 12369; Year: 2011; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

9

(2011) CST Curation Set: 12370; Year: 2011; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

10

(2011) CST Curation Set: 12372; Year: 2011; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

11

(2011) CST Curation Set: 12373; Year: 2011; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

12

(2011) CST Curation Set: 12374; Year: 2011; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

13

(2011) CST Curation Set: 11905; Year: 2011; Biosample: NCI-H1650; Disease: non-small cell lung cancer; Treatment: normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

14

(2011) CST Curation Set: 11906; Year: 2011; Biosample: NCI-H1650; Disease: non-small cell lung cancer; Treatment: normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

15

(2011) CST Curation Set: 11912; Year: 2011; Biosample: HCT116; Disease: colorectal carcinoma; Treatment: normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

16

(2011) CST Curation Set: 11918; Year: 2011; Biosample: NCI-H1650; Disease: non-small cell lung cancer; Treatment: normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

17

(2011) CST Curation Set: 11925; Year: 2011; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

18

(2011) CST Curation Set: 11926; Year: 2011; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

19

(2011) CST Curation Set: 11781; Year: 2011; Biosample: RP98; Disease: non-small cell lung adenocarcinoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

20

(2011) CST Curation Set: 10935; Year: 2011; Biosample: CB-942T; Disease: breast cancer; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

21

Chandarlapaty S, et al. (2011) AKT inhibition relieves feedback suppression of receptor tyrosine kinase expression and activity. Cancer Cell 19, 58-71
21215704   Curated Info

22

(2010) CST Curation Set: 10743; Year: 2010; Biosample: OVKATE; Disease: ovarian cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

23

(2010) CST Curation Set: 10752; Year: 2010; Biosample: OVSAHO; Disease: ovarian cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

24

(2010) CST Curation Set: 10754; Year: 2010; Biosample: OVMIU; Disease: ovarian cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

25

Iliuk AB, et al. (2010) In-depth analyses of kinase-dependent tyrosine phosphoproteomes based on metal ion-functionalized soluble nanopolymers. Mol Cell Proteomics 9, 2162-72
20562096   Curated Info

26

Nakachi I, et al. (2010) The combination of multiple receptor tyrosine kinase inhibitor and mammalian target of rapamycin inhibitor overcomes erlotinib resistance in lung cancer cell lines through c-Met inhibition. Mol Cancer Res 8, 1142-51
20647329   Curated Info

27

Chuang TD, et al. (2010) Human prostatic acid phosphatase, an authentic tyrosine phosphatase, dephosphorylates ErbB-2 and regulates prostate cancer cell growth. J Biol Chem 285, 23598-606
20498373   Curated Info

28

(2010) CST Curation Set: 9858; Year: 2010; Biosample: K562; Disease: chronic myelogenous leukemia; Treatment: normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

29

(2010) CST Curation Set: 9859; Year: 2010; Biosample: K562; Disease: chronic myelogenous leukemia; Treatment: normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

30

(2010) CST Curation Set: 9856; Year: 2010; Biosample: K562; Disease: chronic myelogenous leukemia; Treatment: normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

31

(2010) CST Curation Set: 9345; Year: 2010; Biosample: Kyse30; Disease: esophageal carcinoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

32

(2010) CST Curation Set: 9224; Year: 2010; Biosample: Kyse70; Disease: esophageal carcinoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

33

(2010) CST Curation Set: 9107; Year: 2010; Biosample: NTERA-2; Disease: -; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-102) Cat#: 9416
Curated Info

34

(2010) CST Curation Set: 9099; Year: 2010; Biosample: MGH-xeno5; Disease: ovarian cancer; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

35

Moritz A, et al. (2010) Akt-RSK-S6 Kinase Signaling Networks Activated by Oncogenic Receptor Tyrosine Kinases. Sci Signal 3, ra64
20736484   Curated Info

36

(2009) CST Curation Set: 8108; Year: 2009; Biosample: FAC-7P1; Disease: non-small cell lung adenocarcinoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

37

Marcotte R, et al. (2009) c-Src associates with ErbB2 through an interaction between catalytic domains and confers enhanced transforming potential. Mol Cell Biol 29, 5858-71
19704002   Curated Info

38

Zhong D, et al. (2009) The Glycolytic Inhibitor 2-Deoxyglucose Activates Multiple Prosurvival Pathways through IGF1R. J Biol Chem 284, 23225-33
19574224   Curated Info

39

(2009) CST Curation Set: 7712; Year: 2009; Biosample: HL168; Disease: non-small cell lung cancer; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

40

(2009) CST Curation Set: 7353; Year: 2009; Biosample: HepG2; Disease: hepatocellular carcinoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

41

(2009) CST Curation Set: 7219; Year: 2009; Biosample: BT-474; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

42

(2009) CST Curation Set: 7220; Year: 2009; Biosample: MDA-MB361; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

43

(2009) CST Curation Set: 7156; Year: 2009; Biosample: NCI-H1703; Disease: non-small cell lung cancer; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

44

(2009) CST Curation Set: 6421; Year: 2009; Biosample: YAC-13; Disease: melanoma skin cancer; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

45

Monje PV, Athauda G, Wood PM (2008) Protein kinase A-mediated gating of neuregulin-dependent ErbB2-ErbB3 activation underlies the synergistic action of cAMP on Schwann cell proliferation. J Biol Chem 283, 34087-100
18799465   Curated Info

46

(2008) CST Curation Set: 3920; Year: 2008; Biosample: OCUM-1; Disease: gastric cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

47

(2008) CST Curation Set: 3917; Year: 2008; Biosample: IM95; Disease: gastric cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

48

(2008) CST Curation Set: 3919; Year: 2008; Biosample: NUGC-3; Disease: gastric cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

49

(2008) CST Curation Set: 3792; Year: 2008; Biosample: MKN-7; Disease: gastric cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

50

Guo A, et al. (2008) Signaling networks assembled by oncogenic EGFR and c-Met. Proc Natl Acad Sci U S A 105, 692-7
18180459   Curated Info

51

Rikova K, et al. (2007) Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 131, 1190-203
18083107   Curated Info

52

(2007) CST Curation Set: 2881; Year: 2007; Biosample: HCC202; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

53

(2007) CST Curation Set: 2882; Year: 2007; Biosample: HCC202; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

54

(2007) CST Curation Set: 2686; Year: 2007; Biosample: CAMA-1; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

55

(2007) CST Curation Set: 2688; Year: 2007; Biosample: HCC1187; Disease: breast ductal carcinoma; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

56

(2007) CST Curation Set: 2693; Year: 2007; Biosample: UACC-893; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

57

(2007) CST Curation Set: 2466; Year: 2007; Biosample: HCC1569; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

58

(2007) CST Curation Set: 2467; Year: 2007; Biosample: HCC1569; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

59

(2007) CST Curation Set: 2379; Year: 2007; Biosample: HCC1419; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

60

(2007) CST Curation Set: 2380; Year: 2007; Biosample: HCC1419; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

61

Mullen P, et al. (2007) Sensitivity to pertuzumab (2C4) in ovarian cancer models: cross-talk with estrogen receptor signaling. Mol Cancer Ther 6, 93-100
17237269   Curated Info

62

Xu W, et al. (2007) Loss of Hsp90 association up-regulates Src-dependent ErbB2 activity. Mol Cell Biol 27, 220-8
17030621   Curated Info

63

(2006) CST Curation Set: 2107; Year: 2006; Biosample: HCC1599; Disease: breast cancer; Treatment: 0.5% serum; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

64

(2006) CST Curation Set: 2108; Year: 2006; Biosample: HCC1599; Disease: breast cancer; Treatment: 0.5% serum; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

65

(2006) CST Curation Set: 2109; Year: 2006; Biosample: UACC-812; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

66

(2006) CST Curation Set: 2110; Year: 2006; Biosample: UACC-812; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

67

(2006) CST Curation Set: 2101; Year: 2006; Biosample: 639L; Disease: kidney cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

68

(2006) CST Curation Set: 2103; Year: 2006; Biosample: SW780; Disease: bladder cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

69

(2006) CST Curation Set: 1986; Year: 2006; Biosample: AU565; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

70

(2006) CST Curation Set: 1987; Year: 2006; Biosample: AU565; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

71

(2006) CST Curation Set: 1990; Year: 2006; Biosample: HCC38; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

72

(2006) CST Curation Set: 1991; Year: 2006; Biosample: HCC38; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

73

(2006) CST Curation Set: 1996; Year: 2006; Biosample: ZR-75-30; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

74

(2006) CST Curation Set: 1997; Year: 2006; Biosample: ZR-75-30; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

75

(2006) CST Curation Set: 1934; Year: 2006; Biosample: HD-MyZ; Disease: Hodgkin's lymphoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

76

Wolf-Yadlin A, et al. (2006) Effects of HER2 overexpression on cell signaling networks governing proliferation and migration. Mol Syst Biol 2, 54
17016520   Curated Info

77

(2006) CST Curation Set: 1861; Year: 2006; Biosample: JIMT-1; Disease: breast ductal carcinoma; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

78

(2006) CST Curation Set: 1813; Year: 2006; Biosample: EFM-19; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

79

(2006) CST Curation Set: 1735; Year: 2006; Biosample: EFM-192A; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

80

(2006) CST Curation Set: 1736; Year: 2006; Biosample: HDQ-P1; Disease: breast ductal carcinoma; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

81

(2006) CST Curation Set: 1717; Year: 2006; Biosample: PC9-IR; Disease: non-small cell lung cancer; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

82

(2006) CST Curation Set: 1720; Year: 2006; Biosample: PC9; Disease: non-small cell lung cancer; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

83

(2006) CST Curation Set: 1701; Year: 2006; Biosample: EVSA-T; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

84

(2006) CST Curation Set: 1702; Year: 2006; Biosample: JIMT-1; Disease: breast ductal carcinoma; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

85

(2006) CST Curation Set: 1695; Year: 2006; Biosample: CAL-85-1; Disease: breast adenocarcinoma; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

86

(2006) CST Curation Set: 1698; Year: 2006; Biosample: KPL-1; Disease: breast cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

87

(2006) CST Curation Set: 1629; Year: 2006; Biosample: AGS; Disease: gastric carcinoma; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

88

(2006) CST Curation Set: 1560; Year: 2006; Biosample: SKOV-3; Disease: ovarian epithelial carcinoma; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

89

Bose R, et al. (2006) Phosphoproteomic analysis of Her2/neu signaling and inhibition. Proc Natl Acad Sci U S A 103, 9773-8
16785428   Curated Info

90

(2006) CST Curation Set: 1510; Year: 2006; Biosample: SKOV-3; Disease: ovarian epithelial carcinoma; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

91

(2006) CST Curation Set: 1395; Year: 2006; Biosample: Kyse510; Disease: esophageal carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

92

(2005) CST Curation Set: 962; Year: 2005; Biosample: NCI-H1869; Disease: non-small cell lung cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

93

(2005) CST Curation Set: 885; Year: 2005; Biosample: NCI-H1666; Disease: non-small cell lung cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

94

(2005) CST Curation Set: 886; Year: 2005; Biosample: HCC827; Disease: non-small cell lung cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

95

(2005) CST Curation Set: 887; Year: 2005; Biosample: Calu-3; Disease: lung cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

96

(2005) CST Curation Set: 888; Year: 2005; Biosample: NCI-H3255; Disease: non-small cell lung cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

97

(2005) CST Curation Set: 776; Year: 2005; Biosample: SKBr3; Disease: breast adenocarcinoma; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

98

(2005) CST Curation Set: 647; Year: 2005; Biosample: NCI-H3255; Disease: non-small cell lung cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

99

(2005) CST Curation Set: 627; Year: 2005; Biosample: N87; Disease: gastric carcinoma; Treatment: serum starved & EGF; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

100

(2005) CST Curation Set: 613; Year: 2005; Biosample: NCI-H2170; Disease: non-small cell squamous cell lung carcinoma; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

101

(2005) CST Curation Set: 548; Year: 2005; Biosample: Calu-3; Disease: lung cancer; Treatment: serum starved; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

102

Montgomery RB, et al. (2005) Endogenous anti-HER2 antibodies block HER2 phosphorylation and signaling through extracellular signal-regulated kinase. Cancer Res 65, 650-6
15695410   Curated Info

103

(2003) CST Curation Set: 7915; Year: 2004; Biosample: NCI-H1650; Disease: non-small cell lung cancer; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

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