Ser721

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Phosphorylation Site Page:

Ser721 - p90RSK (mouse)

Site Information

RRVRKLPsTTL____ SwissProt Entrez-Gene

Orthologous residues: p90RSK (rat): S732, p90RSK (human): S732, p90RSK iso3 (mouse): ‑, p90RSK iso3 (human): S741, p90RSK (chicken): S749

Blast this site against: NCBI SwissProt PDB

In vivo Characterization

Methods used to characterize site in vivo:	mass spectrometry (2)
Relevant cell line - cell type - tissue:	32Dcl3 (myeloid) [FLT3 (mouse), transfection, chimera with human FLT3-ITD mutant (corresponding to wild type P36888 ~aa 525-695 ETILLNS...IFEYCC)] (2)

	References

(2010) CST Curation Set: 9665; Year: 2010; Biosample: F9; Disease: testicular cancer; Treatment: untreated; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-RXX(s/t)(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info

Choudhary C, et al. (2009) Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes. Mol Cell 36, 326-39
19854140 Curated Info

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