Ser962
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Phosphorylation Site Page:
Ser962 - CD45 (mouse)

Site Information
NKKKNRNsNVVPYDF    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: CD45 (rat): S944, CD45 (human): S973
Blast this site against: NCBI  SwissProt  PDB 

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3, 4, 5, 6, 7, 8, 9)
Disease tissue studied: anthrax (2), melanoma skin cancer (7)
Relevant cell line - cell type - tissue: 'fat, brown'-'fat, brown' (3), brain (1, 3, 5), heart (3), Hepa 1-6 (epithelial) (8), kidney (3), liver (3, 9), lung (3), macrophage-bone marrow (4), macrophage-bone marrow [MKP-1 (mouse), homozygous knockout] (4), pancreas (3), RAW 267.4 (macrophage) (6), skin [mGluR1 (mouse), transgenic, TG mutant mice] (7), spleen (2, 3), testis (3)




References

1

Trinidad JC, et al. (2012) Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse. Mol Cell Proteomics 11, 215-29
22645316   Curated Info

2

Manes NP, et al. (2011) Discovery of mouse spleen signaling responses to anthrax using label-free quantitative phosphoproteomics via mass spectrometry. Mol Cell Proteomics 10, M110.000927
21189417   Curated Info

3

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

4

Weintz G, et al. (2010) The phosphoproteome of toll-like receptor-activated macrophages. Mol Syst Biol 6, 371
20531401   Curated Info

5

Wiśniewski JR, et al. (2010) Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology. J Proteome Res 9, 3280-9
20415495   Curated Info

6

Trost M, et al. (2009) The phagosomal proteome in interferon-gamma-activated macrophages. Immunity 30, 143-54
19144319   Curated Info

7

Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26
19367708   Curated Info

8

Pan C, Gnad F, Olsen JV, Mann M (2008) Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors. Proteomics 8, 4534-46
18846507   Curated Info

9

Villén J, Beausoleil SA, Gerber SA, Gygi SP (2007) Large-scale phosphorylation analysis of mouse liver. Proc Natl Acad Sci U S A 104, 1488-93
17242355   Curated Info

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