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Phosphorylation Site Page:
Ser16 - DCK (mouse)

Site Information
CPSPSTSsEGTRIKK    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: DCK (rat): S16, DCK (human): S16
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4707236

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3, 4)
Relevant cell line - cell type - tissue: '3T3-L1, differentiated' (adipocyte) (1), brain (4), kidney (4), lung (4), MEF (fibroblast) [p53 (mouse), homozygous knockout] (2), MEF (fibroblast) [TSC2 (mouse), homozygous knockout] (3), pancreas (4), spleen (4)

Controlled by
Treatments: insulin (1), MK-2206 (1)



Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info


Hsu PP, et al. (2011) The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-22
21659604   Curated Info


Yu Y, et al. (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332, 1322-6
21659605   Curated Info


Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

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