Ser458
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Phosphorylation Site Page:
Ser458 - NCL (human)

Site Information
GTEIDGRsISLYYTG    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: NCL (mouse): S460, NCL iso6 (rat): S463, NCL (rat): S462
Blast this site against: NCBI  SwissProt  PDB 

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 4)
Disease tissue studied: cervical cancer (4), cervical adenocarcinoma (4)
Relevant cell line - cell type - tissue: HeLa (cervical) (1, 2), HeLa S3 (cervical) (4), K562 (erythroid) (2)




References

1

Sharma K, et al. (2014) Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling. Cell Rep
25159151   Curated Info

2

Zhou H, et al. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome. J Proteome Res 12, 260-71
23186163   Curated Info

3

Rigbolt KT, et al. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Sci Signal 4, rs3
21406692   Curated Info

4

Olsen JV, et al. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal 3, ra3
20068231   Curated Info

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