Ser1899
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Phosphorylation Site Page:
Ser1899 - ATM (mouse)

Site Information
PANSDSEsENFLRCC    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: ATM (human): S1893, ATM (rat): S1900
Blast this site against: NCBI  SwissProt  PDB 

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1), mutation of modification site (2)
Disease tissue studied: melanoma skin cancer (1)
Relevant cell line - cell type - tissue: B lymphocyte-spleen (2), B16 (melanocyte) (1)


Downstream Regulation
Effects of modification on biological processes: chromatin organization, altered (2)


References

1

Kozlov SV, et al. (2011) Autophosphorylation and ATM activation: additional sites add to the complexity. J Biol Chem 286, 9107-19
21149446   Curated Info

2

Daniel JA, et al. (2008) Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo. J Cell Biol 183, 777-83
19047460   Curated Info

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