Ser740
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Phosphorylation Site Page:
Ser740 - CD44 (mouse)

Site Information
SELNGEAsKSQEMVH    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: CD44 (human): S704, CD44 iso2 (mouse): S325, CD44 iso12 (human): S323, CD44 iso30 (human): S704, CD44 (rat): S465
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 465561

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3)
Disease tissue studied: leukemia (2), acute myelogenous leukemia (2), melanoma skin cancer (3)
Relevant cell line - cell type - tissue: blood (2), macrophage-peritoneum (1), macrophage-peritoneum [RIP3 (mouse), homozygous knockout] (1), skin [mGluR1 (mouse), transgenic, TG mutant mice] (3)




References

1

Wu X, et al. (2012) Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Mol Cell Proteomics 11, 1640-51
22942356   Curated Info

2

Trost M, et al. (2012) Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia. Blood 120, e17-27
22802335   Curated Info

3

Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26
19367708   Curated Info

4

(2008) CST Curation Set: 4770; Year: 2008; Biosample/Treatment: cell line, Dana Farber-S3/untreated; Disease: -; SILAC: -; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-RXX(s/t)(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info

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