Ser733
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Phosphorylation Site Page:
Ser733 - CD44 (mouse)

Site Information
TVEDRKPsELNGEAS    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: CD44 (human): S697, CD44 (rat): S458, CD44 iso2 (mouse): S318
Blast this site against: NCBI  SwissProt  PDB 

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3, 4, 5, 6, 7)
Disease tissue studied: anthrax (2), melanoma skin cancer (6)
Relevant cell line - cell type - tissue: Hepa 1-6 (epithelial) (7), lung (3), macrophage-bone marrow (4), macrophage-bone marrow [MKP-1 (mouse), homozygous knockout] (4), MEF (fibroblast) [p53 (mouse), homozygous knockout] (1), RAW 267.4 (macrophage) (5), skin [mGluR1 (mouse), transgenic, TG mutant mice] (6), spleen (2, 3)

Controlled by
Treatments: LPS (4)



References

1

Hsu PP, et al. (2011) The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-22
21659604   Curated Info

2

Manes NP, et al. (2011) Discovery of mouse spleen signaling responses to anthrax using label-free quantitative phosphoproteomics via mass spectrometry. Mol Cell Proteomics 10, M110.000927
21189417   Curated Info

3

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

4

Weintz G, et al. (2010) The phosphoproteome of toll-like receptor-activated macrophages. Mol Syst Biol 6, 371
20531401   Curated Info

5

Trost M, et al. (2009) The phagosomal proteome in interferon-gamma-activated macrophages. Immunity 30, 143-54
19144319   Curated Info

6

Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26
19367708   Curated Info

7

Pan C, Gnad F, Olsen JV, Mann M (2008) Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors. Proteomics 8, 4534-46
18846507   Curated Info

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