Ser1762
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Phosphorylation Site Page:
Ser1762 - ITGB4 (human)

Site Information
PLQSEYSsITTTHTS    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: ITGB4 iso3 (mouse): S1746, ITGB4 (mouse): S1758, ITGB4 iso3 (human): S1745, ITGB4 iso2 (human): S1692, ITGB4 (rat): T1746, ITGB4 iso2 (mouse): S1693
Blast this site against: NCBI  SwissProt  PDB 

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2)
Disease tissue studied: breast cancer (2), gastric cancer (1), gastric carcinoma (1)
Relevant cell line - cell type - tissue: MCF10A1 (epithelial) (2), MCF10AT1K (epithelial) (2), MCF10CA1a (epithelial) (2), MCF10CA1h (epithelial) (2), MKN-45 (gastric) (1)




References

1

(2010) CST Curation Set: 9790; Year: 2010; SILAC: N; Biosample/Treatment: MKN-45(cell line)/untreated; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

2

Chen Y, et al. (2007) Differential expression of novel tyrosine kinase substrates during breast cancer development. Mol Cell Proteomics 6, 2072-87
17855441   Curated Info

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