Ser85
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Phosphorylation Site Page:
Ser85 - SFRS10 (mouse)

Site Information
HRRSRSRsYSRDYRR    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: SFRS10 (human): S85, SFRS10 (rat): S85
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3193502

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3, 4, 5)
Disease tissue studied: melanoma skin cancer (5)
Relevant cell line - cell type - tissue: brain (4), macrophage-bone marrow (3), macrophage-bone marrow [MKP-1 (mouse), homozygous knockout] (3), MEF (fibroblast) [TSC2 (mouse), homozygous knockout] (1), skin [mGluR1 (mouse), transgenic, TG mutant mice] (5), spleen (2)




References

1

Yu Y, et al. (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332, 1322-6
21659605   Curated Info

2

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

3

Weintz G, et al. (2010) The phosphoproteome of toll-like receptor-activated macrophages. Mol Syst Biol 6, 371
20531401   Curated Info

4

Wiƛniewski JR, et al. (2010) Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology. J Proteome Res 9, 3280-9
20415495   Curated Info

5

Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26
19367708   Curated Info

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