Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Phosphorylation Site Page:
Ser1217 - InsR (human)

Site Information
DGVFTTSsDMWSFGV    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: InsR (mouse): S1207, InsR (rat): S1218, InsR iso2 (human): S1205
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3103702

In vivo Characterization
Methods used to characterize site in vivo: [32P] bio-synthetic labeling (1), immunoprecipitation (1), mutation of modification site (1), phospho-antibody (1), western blotting (1)
Relevant cell line - cell type - tissue: 293 (epithelial) (1), 3T3 (fibroblast) [InsR (human)] (1)

Downstream Regulation
Effects of modification on InsR: enzymatic activity, induced (1)



Bossenmaier B, et al. (2000) Serine residues 1177/78/82 of the insulin receptor are required for substrate phosphorylation but not autophosphorylation. Diabetes 49, 889-95
10866039   Curated Info

Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.