Javascript is not enabled on this browser. This site will not work properly without Javascript.
 |
In vivo Characterization |
 |
| Methods used to characterize site in vivo: |
mass spectrometry (1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 13, 14, 15, 16), phospho-antibody (11), western blotting (11)
|
| Disease tissue studied: |
FTLD (6)
|
| Relevant cell line - cell type - tissue: |
'brain, cortex' (6), Jurkat (T lymphocyte) (1, 2, 3, 4, 5, 7, 8, 9, 10, 14, 15, 16), MKN-45 (gastric) (12, 13), neuron-brain (11)
|
|
|
1
|
(2011) CST Curation Set: 12677; Year: ; Biosample: Jurkat; Disease: T cell leukemia; Treatment: calyculin & pervanadate; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-(F/Y/M)X(s/t)(L/I/M)(phosphorylation)
Curated Info
|
|
2
|
(2011) CST Curation Set: 12681; Year: ; Biosample: Jurkat; Disease: T cell leukemia; Treatment: calyculin & pervanadate; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-(F/Y/M)X(s/t)(L/I/M)(phosphorylation)
Curated Info
|
|
3
|
(2011) CST Curation Set: 12438; Year: 2011; Biosample: Jurkat; Disease: T cell leukemia; Treatment: calyculin & pervanadate; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-(s/t)P(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-(Ser) CDKs Substrate Antibody Cat#: 2324, PTMScan(R) Phospho-CDK Substrate Motif (K/RS*PXK/R) Immunoaffinity Beads Cat#: 1981
Curated Info
|
|
4
|
(2011) CST Curation Set: 11986; Year: 2011; Biosample: Jurkat; Disease: T cell leukemia; Treatment: calyculin & pervanadate; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-(s/t)XP(phosphorylation)
Curated Info
|
|
5
|
(2011) CST Curation Set: 11987; Year: 2011; Biosample: Jurkat; Disease: T cell leukemia; Treatment: calyculin & pervanadate; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-(s/t)XP(phosphorylation)
Curated Info
|
|
6
|
Herskowitz JH, et al. (2010) Phosphoproteomic Analysis Reveals Site-Specific Changes in GFAP and NDRG2 Phosphorylation in Frontotemporal Lobar Degeneration. J Proteome Res 9, 6368-79
20886841
Curated Info
|
|
7
|
(2010) CST Curation Set: 9695; Year: 2010; Biosample: Jurkat; Disease: T cell leukemia; Treatment: pervanadate & calyculin; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-YX(s/t)(phosphorylation)
Curated Info
|
|
8
|
(2010) CST Curation Set: 9642; Year: 2010; Biosample: Jurkat; Disease: T cell leukemia; Treatment: pervanadate & calyculin; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-sPX(I/L/M/V)(phosphorylation)
Curated Info
|
|
9
|
(2009) CST Curation Set: 7652; Year: 2009; Biosample: Jurkat; Disease: T cell leukemia; Treatment: pervanadate & calyculin; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-YX(s/t)(phosphorylation)
Curated Info
|
|
10
|
Mayya V, et al. (2009) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. Sci Signal 2, ra46
19690332
Curated Info
|
|
11
|
Rahman A, et al. (2009) The excitotoxin quinolinic acid induces tau phosphorylation in human neurons. PLoS One 4, e6344
19623258
Curated Info
|
|
12
|
(2008) CST Curation Set: 5570; Year: 2008; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: Su11274; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-(s/t)P(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-(Ser) CDKs Substrate Antibody Cat#: 2324, PTMScan(R) Phospho-CDK Substrate Motif (K/RS*PXK/R) Immunoaffinity Beads Cat#: 1981
Curated Info
|
|
13
|
(2008) CST Curation Set: 5571; Year: 2008; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: Su11274; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-(s/t)P(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-(Ser) CDKs Substrate Antibody Cat#: 2324, PTMScan(R) Phospho-CDK Substrate Motif (K/RS*PXK/R) Immunoaffinity Beads Cat#: 1981
Curated Info
|
|
14
|
(2008) CST Curation Set: 4704; Year: 2008; Biosample: Jurkat; Disease: T cell leukemia; Treatment: calyculin & pervanadate; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-(s/t)P(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-(Ser) CDKs Substrate Antibody Cat#: 2324, PTMScan(R) Phospho-CDK Substrate Motif (K/RS*PXK/R) Immunoaffinity Beads Cat#: 1981
Curated Info
|
|
15
|
(2008) CST Curation Set: 4347; Year: 2008; Biosample: Jurkat; Disease: T cell leukemia; Treatment: pervanadate & calyculin; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-(s/t)P(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-(Ser) CDKs Substrate Antibody Cat#: 2324, Phospho-MAPK/CDK Substrates (PXSP or SPXR/K) (34B2) Rabbit mAb Cat#: 2325, Phospho-(Ser/Thr) PKD Substrate Antibody Cat#: 4381
Curated Info
|
|
16
|
(2008) CST Curation Set: 3882; Year: 2008; Biosample: Jurkat; Disease: T cell leukemia; Treatment: pervanadate; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-[sty](phosphorylation)
Curated Info
|
|
17
|
Liu F, et al. (2002) Aberrant glycosylation modulates phosphorylation of tau by protein kinase A and dephosphorylation of tau by protein phosphatase 2A and 5. Neuroscience 115, 829-37
12435421
Curated Info
|
