Tyr1005
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Phosphorylation Site Page:
Tyr1005 - HER2 (human)

Site Information
SPLDSTFyRSLLEDD    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: HER2 iso2 (human): Y395, HER2 (rat): Y1007, HER2 (mouse): Y1006
Blast this site against: NCBI  SwissProt  PDB 
Available spectra:  1 CST

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61)
Disease tissue studied: breast cancer (29, 30, 38, 39, 40, 41, 42, 43, 44, 45, 48, 58), breast adenocarcinoma (58), colorectal cancer (50), colorectal carcinoma (50), esophageal cancer (26, 55), esophageal carcinoma (26), gastric cancer (1, 2, 3, 4, 5, 7, 8, 9, 11, 12, 17, 23, 24, 25, 27, 35, 36, 51), gastric carcinoma (1, 2, 3, 4, 5, 7, 8, 9, 11, 12, 17, 23, 24, 25, 27, 36), leukemia (18, 19, 20, 21, 22), chronic myelogenous leukemia (18, 19, 20, 21, 22), lung cancer (10, 37, 46, 49, 56, 57, 60, 61), non-small cell lung cancer (10, 37, 46, 49, 57, 60), non-small cell lung adenocarcinoma (10), non-small cell squamous cell lung carcinoma (60), oropharyngeal cancer (54), squamous cell carcinoma of the oropharynx (54), ovarian cancer (52, 53), ovarian epithelial carcinoma (52, 53), melanoma skin cancer (31)
Relevant cell line - cell type - tissue: AU565 (breast cell) (42, 43), BT-474 (breast cell) (29), Calu-3 (pulmonary) (37, 56, 61), Detroit562 (squamous) (54), EFM-192A (breast cell) (48), HCC202 (breast cell) (38, 39), HCC78 (pulmonary) (10, 37, 57), HeLa (cervical) (28), HMEC (endothelial) (47), HMEC 24H (endothelial) (47), HT-29 (intestinal) (50), Jurkat (T lymphocyte) (34), K562 (erythroid) (18, 19, 20, 21, 22), Kyse410 (esophageal) (26), Kyse510 (esophageal) (55), MDA-MB361 (breast cell) (30), MKN-45 (gastric) (1, 2, 3, 4, 5, 7, 8, 9, 11, 12, 17, 23, 24, 25, 27, 33, 36, 51), N87 (gastric) (59), NCI-H1781 (pulmonary) (46), NCI-H2170 (squamous) (37, 60), NCI-H2342 (pulmonary) (49), NUGC-4 (gastric) (35), SKBr3 (breast cell) (58), skin (31), SKOV-3 (ovarian) (52, 53), UACC-812 (breast cell) (40, 41), ZR-75-30 (breast cell) (44, 45)




References

1

(2011) CST Curation Set: 12645; Year: 2011; SILAC: N; Biosample/Treatment: MKN-45(cell line)/untreated; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

2

(2011) CST Curation Set: 12853; Year: 2011; SILAC: N; Biosample/Treatment: MKN-45(cell line)/untreated; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

3

(2011) CST Curation Set: 12854; Year: 2011; SILAC: N; Biosample/Treatment: MKN-45(cell line)/untreated; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

4

(2011) CST Curation Set: 12516; Year: 2011; SILAC: N; Biosample/Treatment: MKN-45(cell line)/normal; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

5

(2011) CST Curation Set: 12519; Year: 2011; SILAC: N; Biosample/Treatment: MKN-45(cell line)/normal; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

6

(2011) CST Curation Set: 12369; Year: 2011; SILAC: N; Biosample/Treatment: MKN-45(cell line)/untreated; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

7

(2011) CST Curation Set: 12370; Year: 2011; SILAC: N; Biosample/Treatment: MKN-45(cell line)/untreated; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

8

(2011) CST Curation Set: 12371; Year: 2011; SILAC: N; Biosample/Treatment: MKN-45(cell line)/untreated; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

9

(2011) CST Curation Set: 11914; Year: 2011; SILAC: N; Biosample/Treatment: MKN-45(cell line)/normal; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

10

(2011) CST Curation Set: 11922; Year: 2011; SILAC: N; Biosample/Treatment: HCC78(cell line)/normal; Disease: non-small cell lung cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

11

(2011) CST Curation Set: 11925; Year: 2011; SILAC: N; Biosample/Treatment: MKN-45(cell line)/normal; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

12

(2011) CST Curation Set: 11926; Year: 2011; SILAC: N; Biosample/Treatment: MKN-45(cell line)/normal; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

13

(2011) CST Curation Set: 11781; Year: 2011; SILAC: N; Biosample/Treatment: RP98(tissue)/untreated; Disease: non-small cell lung adenocarcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

14

(2011) CST Curation Set: 11783; Year: 2011; SILAC: N; Biosample/Treatment: RP100(tissue)/untreated; Disease: non-small cell lung adenocarcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

15

Phanstiel DH, et al. (2011) Proteomic and phosphoproteomic comparison of human ES and iPS cells. Nat Methods 8, 821-7
21983960   Curated Info

16

(2010) CST Curation Set: 10743; Year: 2010; SILAC: N; Biosample/Treatment: OVKATE(cell line)/serum starved; Disease: ovarian cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

17

(2010) CST Curation Set: 10131; Year: 2010; SILAC: N; Biosample/Treatment: MKN-45(cell line)/untreated; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

18

(2010) CST Curation Set: 9955; Year: 2010; SILAC: N; Biosample/Treatment: K562(cell line)/normal; Disease: chronic myelogenous leukemia; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

19

(2010) CST Curation Set: 9954; Year: 2010; SILAC: N; Biosample/Treatment: K562(cell line)/normal; Disease: chronic myelogenous leukemia; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

20

(2010) CST Curation Set: 9953; Year: 2010; SILAC: N; Biosample/Treatment: K562(cell line)/normal; Disease: chronic myelogenous leukemia; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

21

(2010) CST Curation Set: 9859; Year: 2010; SILAC: N; Biosample/Treatment: K562(cell line)/normal; Disease: chronic myelogenous leukemia; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

22

(2010) CST Curation Set: 9857; Year: 2010; SILAC: N; Biosample/Treatment: K562(cell line)/normal; Disease: chronic myelogenous leukemia; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

23

(2010) CST Curation Set: 9788; Year: 2010; SILAC: N; Biosample/Treatment: MKN-45(cell line)/untreated; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

24

(2010) CST Curation Set: 9789; Year: 2010; SILAC: N; Biosample/Treatment: MKN-45(cell line)/untreated; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

25

(2010) CST Curation Set: 9787; Year: 2010; SILAC: N; Biosample/Treatment: MKN-45(cell line)/untreated; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

26

(2010) CST Curation Set: 9229; Year: 2010; SILAC: N; Biosample/Treatment: Kyse410(cell line)/untreated; Disease: esophageal carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

27

(2010) CST Curation Set: 9060; Year: 2010; SILAC: N; Biosample/Treatment: MKN-45(cell line)/Su11274; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

28

(2010) CST Curation Set: 9059; Year: 2010; SILAC: N; Biosample/Treatment: HeLa(cell line)/Peroxide; Disease: cervical adenocarcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

29

(2009) CST Curation Set: 7219; Year: 2009; SILAC: N; Biosample/Treatment: BT-474(cell line)/serum starved; Disease: breast cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

30

(2009) CST Curation Set: 7220; Year: 2009; SILAC: N; Biosample/Treatment: MDA-MB361(cell line)/serum starved; Disease: breast cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

31

(2009) CST Curation Set: 6421; Year: 2009; SILAC: N; Biosample/Treatment: skin(tissue)/untreated; Disease: melanoma skin cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

32

(2009) CST Curation Set: 6385; Year: 2009; SILAC: N; Biosample/Treatment: SNU-308(cell line)/untreated; Disease: bile-duct cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

33

(2008) CST Curation Set: 5771; Year: 2008; SILAC: N; Biosample/Treatment: MKN-45(cell line)/Su11274; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

34

(2008) CST Curation Set: 4536; Year: 2008; SILAC: N; Biosample/Treatment: Jurkat(cell line)/pervanadate & calyculin; Disease: T cell leukemia; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

35

(2008) CST Curation Set: 3791; Year: 2008; SILAC: N; Biosample/Treatment: NUGC-4(cell line)/serum starved; Disease: gastric cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

36

Guo A, et al. (2008) Signaling networks assembled by oncogenic EGFR and c-Met. Proc Natl Acad Sci U S A 105, 692-7
18180459   Curated Info

37

Rikova K, et al. (2007) Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 131, 1190-203
18083107   Curated Info

38

(2007) CST Curation Set: 2881; Year: 2007; SILAC: N; Biosample/Treatment: HCC202(cell line)/serum starved; Disease: breast cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

39

(2007) CST Curation Set: 2882; Year: 2007; SILAC: N; Biosample/Treatment: HCC202(cell line)/serum starved; Disease: breast cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

40

(2006) CST Curation Set: 2109; Year: 2006; SILAC: N; Biosample/Treatment: UACC-812(cell line)/serum starved; Disease: breast cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

41

(2006) CST Curation Set: 2110; Year: 2006; SILAC: N; Biosample/Treatment: UACC-812(cell line)/serum starved; Disease: breast cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

42

(2006) CST Curation Set: 1986; Year: 2006; SILAC: N; Biosample/Treatment: AU565(cell line)/serum starved; Disease: breast cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

43

(2006) CST Curation Set: 1987; Year: 2006; SILAC: N; Biosample/Treatment: AU565(cell line)/serum starved; Disease: breast cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

44

(2006) CST Curation Set: 1996; Year: 2006; SILAC: N; Biosample/Treatment: ZR-75-30(cell line)/serum starved; Disease: breast cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

45

(2006) CST Curation Set: 1997; Year: 2006; SILAC: N; Biosample/Treatment: ZR-75-30(cell line)/serum starved; Disease: breast cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

46

(2006) CST Curation Set: 1921; Year: 2006; SILAC: N; Biosample/Treatment: NCI-H1781(cell line)/serum starved; Disease: non-small cell lung cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

47

Wolf-Yadlin A, et al. (2006) Effects of HER2 overexpression on cell signaling networks governing proliferation and migration. Mol Syst Biol 2, 54
17016520   Curated Info

48

(2006) CST Curation Set: 1735; Year: 2006; SILAC: N; Biosample/Treatment: EFM-192A(cell line)/serum starved; Disease: breast cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

49

(2006) CST Curation Set: 1696; Year: 2006; SILAC: N; Biosample/Treatment: NCI-H2342(cell line)/serum starved; Disease: non-small cell lung cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

50

(2006) CST Curation Set: 1639; Year: 2006; SILAC: N; Biosample/Treatment: HT-29(cell line)/untreated & TSA; Disease: colorectal carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

51

(2006) CST Curation Set: 1605; Year: 2006; SILAC: N; Biosample/Treatment: MKN-45(cell line)/untreated; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

52

(2006) CST Curation Set: 1560; Year: 2006; SILAC: N; Biosample/Treatment: SKOV-3(cell line)/serum starved; Disease: ovarian epithelial carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

53

(2006) CST Curation Set: 1510; Year: 2006; SILAC: N; Biosample/Treatment: SKOV-3(cell line)/serum starved; Disease: ovarian epithelial carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

54

(2006) CST Curation Set: 1515; Year: 2006; SILAC: N; Biosample/Treatment: Detroit562(cell line)/serum starved; Disease: squamous cell carcinoma of the oropharynx; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

55

(2006) CST Curation Set: 1395; Year: 2006; SILAC: N; Biosample/Treatment: Kyse510(cell line)/-; Disease: esophageal carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

56

(2005) CST Curation Set: 887; Year: 2005; SILAC: N; Biosample/Treatment: Calu-3(cell line)/serum starved; Disease: lung cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

57

(2005) CST Curation Set: 778; Year: 2005; SILAC: N; Biosample/Treatment: HCC78(cell line)/serum starved; Disease: non-small cell lung cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

58

(2005) CST Curation Set: 776; Year: 2005; SILAC: N; Biosample/Treatment: SKBr3(cell line)/serum starved; Disease: breast adenocarcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

59

(2005) CST Curation Set: 627; Year: 2005; SILAC: N; Biosample/Treatment: N87(cell line)/serum starved & EGF; Disease: gastric carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

60

(2005) CST Curation Set: 613; Year: 2005; SILAC: N; Biosample/Treatment: NCI-H2170(cell line)/serum starved; Disease: non-small cell squamous cell lung carcinoma; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

61

(2005) CST Curation Set: 548; Year: 2005; SILAC: N; Biosample/Treatment: Calu-3(cell line)/serum starved; Disease: lung cancer; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

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