Ser1404

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Phosphorylation Site Page:

Ser1404 - ITGB4 iso2 (human)

Site Information

AAYGTHLsPHVPHRV SwissProt Entrez-Gene

Predicted information: Scansite

Orthologous residues: ITGB4 iso2 (mouse): S1405, ITGB4 (human): S1474, ITGB4 iso3 (mouse): S1405, ITGB4 (mouse): S1470, ITGB4 iso3 (human): S1404, ITGB4 (rat): S1405

Blast this site against: NCBI SwissProt PDB

In vivo Characterization

Methods used to characterize site in vivo:	mass spectrometry (1, 2, 3, 4, 5)
Disease tissue studied:	gastric cancer (5), gastric carcinoma (5)
Relevant cell line - cell type - tissue:	MKN-45 (gastric) (1, 2, 3, 4, 5)

	References

1	(2008) CST Curation Set: 4496; Year: 2008; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: normal & normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-RXX(s/t)(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS/T) Immunoaffinity Beads Cat#: 1978 Curated Info
2	(2008) CST Curation Set: 4484; Year: 2008; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: normal & normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-RXX(s/t)(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS/T) Immunoaffinity Beads Cat#: 1978 Curated Info
3	(2008) CST Curation Set: 4492; Year: 2008; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: normal & normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-RXX(s/t)(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS/T) Immunoaffinity Beads Cat#: 1978 Curated Info
4	(2008) CST Curation Set: 4488; Year: 2008; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: normal & normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-RXX(s/t)(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS/T) Immunoaffinity Beads Cat#: 1978 Curated Info
5	Guo A, et al. (2008) Signaling networks assembled by oncogenic EGFR and c-Met. Proc Natl Acad Sci U S A 105, 692-7 18180459 Curated Info

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1	(2008) CST Curation Set: 4496; Year: 2008; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: normal & normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-RXX(s/t)(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS/T) Immunoaffinity Beads Cat#: 1978 Curated Info
2	(2008) CST Curation Set: 4484; Year: 2008; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: normal & normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-RXX(s/t)(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS/T) Immunoaffinity Beads Cat#: 1978 Curated Info
3	(2008) CST Curation Set: 4492; Year: 2008; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: normal & normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-RXX(s/t)(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS/T) Immunoaffinity Beads Cat#: 1978 Curated Info
4	(2008) CST Curation Set: 4488; Year: 2008; Biosample: MKN-45; Disease: gastric carcinoma; Treatment: normal & normal; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-RXX(s/t)(phosphorylation) Antibody Used to Purify Peptides prior to MS2: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS/T) Immunoaffinity Beads Cat#: 1978 Curated Info
5	Guo A, et al. (2008) Signaling networks assembled by oncogenic EGFR and c-Met. Proc Natl Acad Sci U S A 105, 692-7 18180459 Curated Info