Thr1514
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Phosphorylation Site Page:
Thr1514 - ITGB4 (human)

Site Information
PRDYSTLtSVSSHDS    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: ITGB4 iso3 (mouse): T1445, ITGB4 (mouse): T1510, ITGB4 iso3 (human): T1444, ITGB4 iso2 (human): T1444, ITGB4 (rat): T1445, ITGB4 iso2 (mouse): T1445
Blast this site against: NCBI  SwissProt  PDB 

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (2, 3, 4, 5)
Disease tissue studied: gastric cancer (4), gastric carcinoma (4), leukemia (3), chronic myelogenous leukemia (3)
Relevant cell line - cell type - tissue: Jurkat (T lymphocyte) (2, 5), K562 (erythroid) (3), MKN-45 (gastric) (4)




References

1

Kim JY, et al. (2013) Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells. Proc Natl Acad Sci U S A 110, 12414-9
23836654   Curated Info

2

(2011) CST Curation Set: 12497; Year: 2011; SILAC: N; Biosample/Treatment: Jurkat(cell line)/calyculin & pervanadate; Disease: T cell leukemia; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

3

(2010) CST Curation Set: 9954; Year: 2010; SILAC: N; Biosample/Treatment: K562(cell line)/normal; Disease: chronic myelogenous leukemia; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

4

Guo A, et al. (2008) Signaling networks assembled by oncogenic EGFR and c-Met. Proc Natl Acad Sci U S A 105, 692-7
18180459   Curated Info

5

(2007) CST Curation Set: 2928; Year: 2007; SILAC: N; Biosample/Treatment: Jurkat(cell line)/pervanadate & calyculin; Disease: T cell leukemia; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

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