Thr1514
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Phosphorylation Site Page:
Thr1514 - ITGB4 (human)

Site Information
PRDYSTLtSVSSHDS    SwissProt Entrez-Gene
Predicted information: Scansite
Orthologous residues: ITGB4 iso3 (mouse): T1445, ITGB4 (mouse): T1510, ITGB4 iso3 (human): T1444, ITGB4 iso2 (human): T1444, ITGB4 (rat): T1445, ITGB4 iso2 (mouse): T1445
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2424912

In vivo Characterization
Methods used to characterize site in vivo: mass spectrometry (1, 2, 3, 4)
Disease tissue studied: gastric cancer (3), gastric carcinoma (3), leukemia (2), chronic myelogenous leukemia (2)
Relevant cell line - cell type - tissue: Jurkat (T lymphocyte) (1, 4), K562 (erythroid) (2), MKN-45 (gastric) (3)




References

1

(2011) CST Curation Set: 12497; Year: 2011; Biosample/Treatment: cell line, Jurkat/calyculin & pervanadate; Disease: T cell leukemia; SILAC: -; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

2

(2010) CST Curation Set: 9954; Year: 2010; Biosample/Treatment: cell line, K562/normal; Disease: chronic myelogenous leukemia; SILAC: -; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

3

Guo A, et al. (2008) Signaling networks assembled by oncogenic EGFR and c-Met. Proc Natl Acad Sci U S A 105, 692-7
18180459   Curated Info

4

(2007) CST Curation Set: 2928; Year: 2007; Biosample/Treatment: cell line, Jurkat/pervanadate & calyculin; Disease: T cell leukemia; SILAC: -; Specificity of Antibody Used to Purify Peptides prior to MS2: anti-pTyr Antibody Used to Purify Peptides prior to MS2: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

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